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NBQX
SynDRA canonical compound SYN0006655 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | GRIA1 |
|---|
| Mechanism of action | Glutamate receptor antagonist |
|---|
All known targets
- GRIA1
- GRIA2
- GRIA3
- GRIA4
- GRIK1
- GRIN1
- GRIN2A
- GRIN2B
Mechanisms of action (all sources)
- Glutamate receptor antagonist
- GRIA1 ANTAGONIST
- GRIA2 ANTAGONIST
- GRIA3 ANTAGONIST
- GRIA4 ANTAGONIST
- GRIN1 INHIBITOR
- GRIK1 INHIBITOR
- GRIN2A INHIBITOR
- GRIA1 INHIBITOR
- GRIN2B INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- GRIK3
- GRIK2
- ALDH1A1
- HSD17B10
- KDM4E
- KMT2A
- MAPT
- MBNL1
- PABPC1
- PIN1
- PKM
- POLI
- POLK
- RECQL
- RGS4
- TDP1
- THRB
- TP53
- USP1
- KAT2A
- HPGD
- ALOX15
- CYP2C19
- APEX1
- ARSA
- ATXN2
- BLM
- CBX1
- CYP1A2
- CYP2C9
- HDAC6
- CYP2D6
- CYP3A4
- EHMT2
- GLA
- GMNN
- GRM6
- VDR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP1A2
- FUMH
- G3P
- GRIK4
- GRIK5
- MITF
- NTM1A
- PHGDH
Drug classes
- Anti-Anxiety Agents
- Anticonvulsants
- Excitatory Amino Acid Antagonists
Cross-references
Synonyms
- FG 9202
- 2,3-Dioxo-6-nitro-7-sulfamoylbenzo(f)quinoxaline
- 2,3-Dihydroxy-6-nitro-7-sulfamoyl-benzo(f)quinoxaline
- 6-Nitro-7-sulfamoylbenzo(f)quinoxaline-2,3-dione
- CHEMBL222519
- CHEBI:31073
- SBB066176
- 6-nitro-2,3-dioxo-1,4-dihydrobenzo[f]quinoxaline-7-sulfonamide
- 1,2,3,4-Tetrahydro-6-nitro-2,3-dioxobenzo(f)quinoxaline-8-sulfonamide
- 6-Nitro-7-sulphamoylbenzo[f]quinoxaline-2,3-dione
- 6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-Dione
- 2,3-dihydroxy-6-nitro-7-sulfamoylbenzo(f)quinoxaline
- 8LZ6Q43V2S
- 2,3-Dioxo-6-nitro-7-sulfamoylbenzo[f]quinoxaline
- RefChem:442573
- DTXCID7074747
- MFCD00270054
- 6-Nitro-7-sulfamoylbenzo[f]quinoxaline-2,3-dione; NBQX
- 3-Hydroxy-6-nitro-7-sulfamoyl-benzo[f]quinoxalin-2-ol anion
- Tocris-0373
- NBQX?
- Biomol-NT_000220
- UNII-8LZ6Q43V2S
- Lopac0_000912
- SCHEMBL120375
- SCHEMBL220464
- BPBio1_001312
- C12H8N4O6S
- GTPL4264
- orb1303149
- SCHEMBL9036467
- NBQX (FG9202)
- SCHEMBL29356960
- SCHEMBL29412437
- GLXC-21282
- HMS3266I19
- HMS3411G09
- HMS3675G09
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