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PENICILLAMINE
SynDRA canonical compound SYN0006616 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | chelating agent |
|---|
| Indication | cystinuria | rheumatoid arthritis | Wilson's disease |
|---|
| Disease area | metabolism | nephrology | rheumatology |
|---|
All known targets
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PTGS1
- ABCC2
- KDM4E
- MC5R
- MC4R
- MC3R
- MAPT
- MAPK3
- MAPK14
- MAPK1
- MAOB
- MAOA
- LCK
- KDR
- KDM4A
- MMP9
- KCNH2
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- GMNN
- MMP1
- NPY1R
- ABCC3
- NPY2R
- VDR
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
- SLC6A4
Drug classes
- Antidotes
- Antirheumatic Agents
- Chelating Agents
- Protective Agents
- Sequestering Agents
- Antirheumatic Agent
- chelating agent
ATC classes
- M01C · SPECIFIC ANTIRHEUMATIC AGENTS
Cross-references
Synonyms
- CUPRIMINE
- Cuprimine
- DEPEN
- Depen
- LUXZYLA
- cuprenil
- cuprimine
- cupripen
- D-Mercaptovaline
- D-Penicillamine
- depamine
- pendramine
- Penicilamina
- D-3-mercaptovaline
- Dimethylcysteine
- NSC-758421
- NSC-81549
- D mercaptovaline
- D penicillamine
- Distamine
- Trolovol
- D Penicillamine
- D-(-)-Penicillamine
- 3-Mercapto-D-valine
- Cuprenil
- D-Penamine
- (-)-Penicillamine
- Mercaptovaline
- Perdolat
- Penicillamin
- Pendramine
- Kuprenil
- Depamine
- Mercaptyl
- Metalcaptase
- Artamine
- Cupripen
Reported adverse events
- Leukopenia
- Muscular weakness
- Thrombotic thrombocytopenic purpura
- Thyroiditis
- Tinnitus
- Urticaria
- Goodpasture's syndrome
- Renal failure
- Vasculitis
- Myasthenia gravis
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