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ACYCLOVIR
SynDRA canonical compound SYN0006465 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PNP |
|---|
| Mechanism of action | DNA polymerase inhibitor |
|---|
| Indication | chicken pox | genitial herpes | shingles |
|---|
| Disease area | infectious disease |
|---|
All known targets
- PNP
- HSV UL30
- TK
- VZV ORF28
- punA
Mechanisms of action (all sources)
- DNA polymerase inhibitor
- HSV UL30 MODULATOR
- VZV ORF28 MODULATOR
- TK INHIBITOR
- HSV UL30 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- EDNRA
- TK1
- HTR2A
- ACHE
- NPY1R
- MC4R
- MC5R
- MLNR
- MMP1
- MMP9
- NR3C1
- NPY2R
- MAPK3
- NTSR1
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- MC3R
- MAPK1
- MAPK14
- PDE4D
- MAOA
- LCK
- KDR
- KCNH2
- HTR7
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR1A
- HSD17B10
- HRH3
- HRH2
- PDE4A
- PDE5A
- HMGCR
- SMAD3
- SLC47A2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- DNA Polymerase Inhibitors
- Herpesvirus Nucleoside Analog DNA Polymerase Inhibitor
- Anti-Infective Agents
- Antiviral Agents
- Herpes Simplex Virus Nucleoside Analog DNA Polymerase Inhibitor
- Herpes Zoster Virus Nucleoside Analog DNA Polymerase Inhibitor
- Enzyme Inhibitors
ATC classes
- J05A · DIRECT ACTING ANTIVIRALS
- S01A · ANTIINFECTIVES
- D06B · CHEMOTHERAPEUTICS FOR TOPICAL USE
Cross-references
Synonyms
- ACYCLOVIR IN SODIUM CHLORIDE 0.9% PRESERVATIVE FREE
- ACYCLOVIR SODIUM
- AVACLYR
- Avaclyr
- Lypsyl
- SITAVIG
- Sitavig
- XERESE
- ZOVIRAX
- Zovirax
- zovirax
- aciclovir
- acyclovir sodium
- Aciclovir
- Aciclovirum
- Gerpevir
- Novirus
- NSC-645011
- NSC-758477
- Acycloguanosine
- Acyclovir component of xerese
- Avert
- Clearsore
- Cymex ultra
- Duvimex
- Herpetad
- Lipsore
- Ranovir
- Soothelip
- Soraway
- Viralief
- Virasorb
- Virovir 200
- Virovir 400
- Virovir 800
- Vipral
- Virorax
Reported adverse events
- Nausea
- Myalgia
- Stevens-Johnson syndrome
- Alopecia
- Renal failure
- Angioedema
- Erythema
- Headache
- Rash
- Pruritus
- Abdominal pain
- Disseminated intravascular coagulation
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