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DOMPERIDONE
SynDRA canonical compound SYN0006418 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | DRD3 |
|---|
| Mechanism of action | Dopamine receptor antagonist |
|---|
| Indication | fescue toxicosis |
|---|
| Disease area | infectious disease |
|---|
All known targets
- DRD2
- DRD3
- SLC6A2
- SLC47A2
- SLC47A1
- SLC22A2
- RXRA
- OPRM1
- OPRK1
- KCNH2
- HTR2C
- HTR2B
Mechanisms of action (all sources)
- Dopamine receptor antagonist
- DRD2 ANTAGONIST
- Dopamine D2 receptor antagonist
- DRD3 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- SCN5A
- NR1I2
- PDE4D
- ESR1
- ADRB2
- HTR1A
- SLC6A3
- MMP9
- MC5R
- MLNR
- MMP1
- NFKB1
- MPHOSPH8
- MTOR
- MC3R
- NPY1R
- NPY2R
- MC4R
- ABCC2
- MAPK3
- MAPK14
- NR4A1
- MAPK1
- MAOA
- LMNA
- LCK
- HTR6
- HTR3A
- HRH3
- HRH2
- HMGCR
- HIF1A
- NR3C1
- PDE3A
- OPRD1
- GMNN
- USP2
- TSHR
- TDP1
- TBXAS1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- APAF
- B2CL1
- CP1A2
- CP2D6
- CP3A7
- ESRRA
- GLI3
- JUN
- KSYK
- MCL1
- NSD2
- PPBT
- SMAD2
- SYK
Drug classes
- Antiemetics
- Central Nervous System Agents
- Dopamine Agents
- Dopamine Antagonists
- Gastrointestinal Agents
- Neurotransmitter Agents
- Peripheral Nervous System Agents
ATC classes
Cross-references
Synonyms
- Equidone
- domperidone betadex
- domperidone betacyclodextrin
- motilium
- peridon
- domperidone maleate
- Domperidona
- NSC-299589
- NSC-759575
- R 33,812
- R-33812
- Domilium
- Evoxin
- Motilium
- Motilium 10
- Motilium instants
- Vivadone
- Domperidon
- Domperidonum
- Nauzelin
- KW-5338
- NCI299589
- Costi (TN)
- D-122
- Domperidona [INN-Spanish]
- Domperidonum [INN-Latin]
- HS-0067
- Motilium (TN)
- Motillium (TN)
- Motinorm (TN)
- R-33,812
- Domperidone (JAN/USAN/INN)
- Domperidone [USAN:BAN:INN:JAN]
- C22H24ClN5O2
- R 33812
- NSC299589
- NSC 299589
- R33812
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