← SynDRA
SITAGLIPTIN
SynDRA canonical compound SYN0006393 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | DPP4 |
|---|
| Mechanism of action | Dipeptidyl peptidase inhibitor |
|---|
| Indication | diabetes mellitus |
|---|
| Disease area | endocrinology |
|---|
All known targets
- DPP4
- ACE
- CYP2C8
- DPP IV
- DPP7
- DPP8
- DPP9
- Dpp4
- FAP
- FASLG
- HMGCR
- SLC22A8
Mechanisms of action (all sources)
- Dipeptidyl peptidase inhibitor
- DPP4 inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADORA1
- MC3R
- NTSR1
- NR3C1
- NR1I2
- NPY2R
- NPY1R
- MME
- MLNR
- MC4R
- MAOA
- OPRK1
- KCNH2
- HTR7
- HTR6
- HTR5A
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- OPRD1
- OPRM1
- HRH3
- SLC47A1
- XPNPEP1
- TBXA2R
- TACR2
- TACR1
- SLC6A4
- SLC6A3
- SLC6A2
- SLC47A2
- SLC29A1
- PDE3A
- SETD7
- PTGS2
- PREP
- PPARG
- PGR
- PEPD
Drug classes
- Dipeptidyl-Peptidase IV Inhibitors
- Enzyme Inhibitors
- Hormones
- Hypoglycemic Agents
- Incretins
- Protease Inhibitors
- Dipeptidyl Peptidase 4 Inhibitors
- Dipeptidyl Peptidase 4 Inhibitor
ATC classes
- A10B · BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Cross-references
Synonyms
- BRYNOVIN
- Brynovin
- JANUMET
- JANUMET XR
- JANUVIA
- JUVISYNC
- Janumet
- Januvia
- SITAGLIPTIN AND METFORMIN HYDROCHLORIDE
- SITAGLIPTIN PHOSPHATE
- STEGLUJAN
- Steglujan
- sitagliptin phosphate
- januvia
- ristaben
- sitagliptin phosphate hydrate
- sitagliptin phosphate monohydrate
- MK 0431
- sitagliptin monophosphate monohydrate
- sitagliptin phosphate anhydrous
- sitagliptin hydrochloride monohydrate
- Sitagliptine
- Sitagliptina
- LEZ-763
- LEZ763
- Sitagliptin component of zituvimet
- Xelevia
- Sitagliptan
- MK-0431
- UNII-QFP0P1DV7Z
- Tesavel
- QFP0P1DV7Z
- CHEBI:40237
- Sitagliptin phosphate
- Januvia (TN)
- Sitagliptin (PropINN)
- Januvia (merck & Co)
- Sitagliptin/atovastatin
Reported adverse events
- Stevens-Johnson syndrome
- Arthralgia
- Hypersensitivity
- Headache
- Vomiting
- Nasopharyngitis
- Nausea
- Abdominal discomfort
- Back pain
- Thirst
- Urinary tract infection
- Ketoacidosis
Look up SITAGLIPTIN in the interactive SynDRA portal →