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SARACATINIB
SynDRA canonical compound SYN0006380 — structure-anchored drug synonym record
| Clinical phase | Phase 2/Phase 3 |
|---|
| Primary target(s) | SRC |
|---|
| Mechanism of action | Src inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
- SRC inhibitor
- ABL1 INHIBITOR
- Tyrosine-protein kinase ABL inhibitor
- Tyrosine-protein kinase SRC inhibitor
- LCK INHIBITOR
- YES1 INHIBITOR
- SRC MODULATOR
- ABL1 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- EGFR
- BMPR1A
- GAK
- BTK
- SYK
- PTK6
- DDR2
- DDR1
- STK10
- HCK
- LYN
- PKMYT1
- CDK2
- SLK
- KIT
- SIK3
- SIK2
- RET
- PDGFRA
- PDGFRB
- RIPK2
- RIPK3
- COQ8A
- BMPR1B
- MAP3K20
- FYN
- EPHA2
- FGR
- EPHB6
- EPHB4
- FLT3
- EPHB2
- ACVR1
- ACVR1B
- ACVR2B
- EPHA5
- BCR
- MAP4K4
- TNK2
- EPHA4
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- COMT
- GAMT
- GNMT
- HNMT
- IFNB1
- KSYK
- NNMT
- NSD2
- PNMT
- TP53
Drug classes
- Antineoplastic Agents
- Enzyme Inhibitors
Cross-references
Synonyms
- AZD-0530
- AZ-10353926
- AZD0530
- H8H
- Saracatinib, AZD-0530, AZD0530
- N-(5-Chloro-1,3-benzodioxol-4-yl)-7-(2-(4-methylpiperazin-1-yl)ethoxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine
- Saracatinib (AZD0530)
- AZD 0530
- N-(5-Chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methyl-1-piperazinyl)ethoxy]-5-[(tetrahydro-2H-pyran-4-yl)oxy]-4-quinazolinamine
- SARACATINIB, FREE BASE
- N-(5-chlorobenzo[d][1,3]dioxol-4-yl)-7-(2-(4-methylpiperazin-1-yl)ethoxy)-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine
- 9KD24QGH76
- CHEMBL217092
- N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(oxan-4-yloxy)quinazolin-4-amine
- N-(5-chloro-1,3-benzodioxol-4-yl)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-(tetrahydro-2H-pyran-4-yloxy)quinazolin-4-amine
- 4-(6-Chloro-2,3-methylenedioxyanilino)-7-(2-(4-methylpiperazin-1-yl)ethoxy)-5-tetrahydropyran-4-yloxyquinazoline
- 4-Quinazolinamine, N-(5-chloro-1,3-benzodioxol-4-yl)-7-(2-(4-methyl-1-piperazinyl)ethoxy)-5-((tetrahydro-2H-pyran-4-yl)oxy)-
- Saracatinib [USAN]
- nchembio866-comp19
- Saracatinib [USAN:INN]
- saracatinibum
- UNII-9KD24QGH76
- 4-(6-chloro-2,3-methylenedioxyanilino)-7-[2-(4-methylpiperazin-1-yl)ethoxy]-5-tetrahydropyran-4-yloxyquinazoline
- 2h8h
- Saracatinib,AZD0530
- SARACATINIB [INN]
- Saracatinib (USAN/INN)
- Saracatinib - AZD0530
- SCHEMBL41547
- SARACATINIB [WHO-DD]
- MLS006011166
- GTPL7731
- BDBM12255
- CHEBI:47458
- AZD0350
- DTXSID90191355
- BCPP000364
- HMS3265E21
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