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PRALIDOXIME
SynDRA canonical compound SYN0006367 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ACHE |
|---|
| Mechanism of action | Acetylcholinesterase inhibitor |
|---|
| Indication | organophosphate poisoning |
|---|
| Disease area | critical care |
|---|
All known targets
Mechanisms of action (all sources)
- Acetylcholinesterase inhibitor
- ACHE ACTIVATOR
- Acetylcholinesterase activator
- ACHE INHIBITOR
- ACHE MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADORA1
- HDAC6
- NR3C1
- NPY2R
- NPY1R
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KDM4E
- KDM4A
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- OPRD1
- OPRK1
- OPRM1
- SLC6A2
- USP1
- TSHR
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SMN1
- SLCO1B3
- SLCO1B1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Cholinesterase Reactivators
- Antidotes
- Cholinergic Agents
- Neurotransmitter Agents
- Protective Agents
- Cholinesterase Reactivator
ATC classes
- V03A · ALL OTHER THERAPEUTIC PRODUCTS
Cross-references
Synonyms
- ATNAA
- DUODOTE
- Duodote
- PRALIDOXIME CHLORIDE
- PRALIDOXIME CHLORIDE (AUTOINJECTOR)
- PROTOPAM CHLORIDE
- Protopam
- pralidoxime iodide
- pralidoxime chloride
- Atnaa
- Pralidoxime cation
- Pralidoxime ion
- P7MU9UTP52
- Spectrum_001144
- Prestwick0_000943
- Prestwick1_000943
- Spectrum2_000921
- Spectrum3_001498
- Spectrum4_000323
- KBioGR_000665
- KBioSS_001624
- DivK1c_000770
- SCHEMBL439969
- SPBio_000822
- SPBio_003065
- N-methyl-pyridinium-2-aldoxime
- GTPL4652
- orb1744464
- SCHEMBL31456539
- KBio1_000770
- KBio2_001624
- KBio2_004192
- KBio2_006760
- KBio3_002615
- JBKPUQTUERUYQE-UHFFFAOYSA-O
- JBKPUQTUERUYQE-VOTSOKGWSA-O
- NINDS_000770
- Pralidoximum
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