NGD-8243

SynDRA canonical compound SYN0006358 — structure-anchored drug synonym record

Clinical phase	Phase 2
Primary target(s)	TRPV1
Mechanism of action	TRPV antagonist

All known targets

TRPV1

Mechanisms of action (all sources)

TRPV1 ANTAGONIST
Vanilloid receptor antagonist
TRPV antagonist
TRPV1 BLOCKER

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

HDAC6
KCNH2
MBD4
MPG
MUTYH
NEIL1
NEIL2
NTHL1
OGG1
SMUG1
TDG
UNG

Cross-references

PubChem CID: 11247522
ChEMBL: CHEMBL214796
TTD: D0Z0PB

Synonyms

MK-2295
MK-2295-005
SCHEMBL17320582
K3S4K8ACHE
UNII-K3S4K8ACHE
RefChem:165627
orb1297860
SCHEMBL2730820
SCHEMBL29706343
VTANGSDRFFLTSQ-UHFFFAOYSA-N
GLXC-20294
BDBM50191726
AKOS015993894
BC-0200
DB-144092
T9818
BRD-K43316319-001-01-8

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