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CICLOPIROX
SynDRA canonical compound SYN0006297 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ATP1A1 |
|---|
| Mechanism of action | Membrane integrity inhibitor |
|---|
| Indication | onychomycosis |
|---|
| Disease area | infectious disease |
|---|
All known targets
Mechanisms of action (all sources)
- Membrane integrity inhibitor
- PARP1 INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD3
- KDM4B
- ESR1
- ESR2
- MC3R
- MAOA
- MAPK1
- MAPK14
- MAPK3
- ABCC2
- LMNA
- MC5R
- MMP1
- MMP9
- NFE2L2
- NPY1R
- NPY2R
- NR1I2
- MC4R
- LCK
- HRH3
- KDR
- KDM4E
- KDM4A
- KCNH2
- KAT2A
- IDO1
- IDH1
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- NR3C1
- OPRD1
- OPRK1
- SLC6A2
- USP1
- TP53
- TDP1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- BARD1
- SMAD2
- PRGR
- PAX8
- NSD2
- MITF
- MDM4
- MDM2
- LOX12
- KSYK
- IFNG
- IDHC
- HSPB1
- HS90A
- GPR32
- GLI3
- GCR
- CREB1
- CP1A2
- BRCA1
- SYK
Drug classes
- Protein Synthesis Inhibitors
- Anti-Infective Agents
- Antifungal Agents
ATC classes
- D01A · ANTIFUNGALS FOR TOPICAL USE
- G01A · ANTIINFECTIVES AND ANTISEPTICS, EXCL. COMBINATIONS WITH CORTICOSTEROIDS
Cross-references
Synonyms
- Ciclodan
- LOPROX
- Loprox
- PENLAC
- penlac
- ciclopirox olamine
- ciclopirox ethanolamine
- Cyclopirox
- HOE-296B
- Penlac
- Ciclopiroxum
- Cyclopyroxolamine
- Stieprox
- Terit
- Ciclopirox-Olamin
- Ciclopirox gel
- Loprox Gel
- Loprox Shampoo
- Loprox cream
- Penlac nail lacquer
- HOE-296b
- Batrafen (TN)
- Ciclopiroxum [INN-Latin]
- Dafnegin-CSC
- HOE-296
- Loprox (TN)
- Penlac (TN)
- Stieprox (TN)
- Ciclopirox (USP/INN)
- Ciclopirox [USAN:BAN:INN]
- cyclopirox
- HOE296b
- Ciclopirox (Penlac)
- 19W019ZDRJ
- CHEBI:453011
- 29342-05-0 (free)
- MLS002153867
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