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PHA-543613
SynDRA canonical compound SYN0006293 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | CHRNA7 |
|---|
| Mechanism of action | nicotinic receptor agonist |
|---|
All known targets
Mechanisms of action (all sources)
- CHRNA7 AGONIST
- Neuronal acetylcholine receptor protein alpha-7 subunit agonist
- CHRNA7 FULL AGONIST
- nicotinic receptor agonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACE
- HRH1
- HTR1A
- HTR1B
- HTR2A
- HTR2C
- HTR5A
- HTR6
- HTR7
- KCNH2
- MAOA
- MAOB
- NOS2
- OPRD1
- OPRK1
- OPRL1
- OPRM1
- PDE2A
- PLA2G1B
- PTGS1
- PTGS2
- SIGMAR1
- SLC6A2
- SLC6A3
- SLC6A4
- TACR1
- TACR2
- TACR3
- TH
- TSPO
- VIPR1
- HRH2
- EGFR
- ACHE
- EDNRB
- ADORA1
- ADORA3
- ADRB1
- ADRB2
- AGTR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP2D6
- HTR3A
- HTR3B
- HTR3C
- HTR3D
- HTR3E
Cross-references
Synonyms
- Pha-00543613
- J3.179.420J
- PHA-543,613
- (R)-N-(Quinuclidin-3-yl)furo(2,3-C)pyridine-5-carboxamide
- R36R9KVD6Y
- PHA-00543613
- DTXCID4027284
- (R)-N-(quinuclidin-3-yl)furo[2,3-c]pyridine-5-carboxamide
- RefChem:860497
- PHA543613
- UNII-R36R9KVD6Y
- GTPL3998
- orb1704236
- SCHEMBL2596554
- CHEBI:167763
- IPKZCLGGYKRDES-ZDUSSCGKSA-N
- EX-A7286
- Tox21_300448
- BDBM50190786
- AKOS005146334
- EBC-224058
- NCGC00248050-01
- NCGC00254368-01
- DA-66649
- MS-23841
- HY-105670
- CAS-478149-53-0
- CS-0026424
- F82142
- T23145
- PHA-543613, >=98% (HPLC)
- N-[(3R)-1-azabicyclo[2.2.2]octan-3-yl]furo[2,3-c]pyridine-5-carboxamide
- 5Qat734klh
- PHA-543613 FUMARATE
- PHA543613F
- PHA-543613F
- PHA 543613E
- DA-76795
- Z7950E6X01
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