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ESTRONE
SynDRA canonical compound SYN0006147 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | ESR1 |
|---|
| Mechanism of action | Estrogen receptor agonist |
|---|
| Indication | menopause |
|---|
| Disease area | endocrinology |
|---|
All known targets
- ESR1
- ESR2
- ALOX15
- Ar
- CYP19A1
- HSD17B1
- HTR2B
- PGR
- SERPINA6
- SHBG
- SLC6A4
- SNCA
Mechanisms of action (all sources)
- ESR1 AGONIST
- ESR1 MODULATOR
- ESR2 AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCG2
- SLC6A3
- AKR1B10
- OPRM1
- PMP22
- PDE5A
- PDE4A
- PDE3A
- POLI
- MMP9
- OPRK1
- OPRD1
- NR3C1
- NPY2R
- NPY1R
- NFKB1
- PPP3CA
- NFE2L2
- MMP1
- PTAFR
- LMNA
- HTR2A
- HTR2C
- HTR6
- KCNH2
- KDR
- LCK
- MAOA
- MC5R
- MAPK1
- MAPK14
- MAPK3
- MAPT
- MC3R
- MC4R
- PRKCA
- ABCB1
- PTGS1
- UGT1A7
- TBXAS1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- COMT
- CP2C9
- CP3A7
- ESRRA
- GAMT
- GCR
- GLI3
- GNMT
- HNMT
- IFNG
- NNMT
- NR1I2
- PNMT
- PRGR
- RARA
Drug classes
- Estrogens
- Hormones
- estrogenic hormone
- Contraceptive Agents
- Contraceptive Agents, Hormonal
- Reproductive Control Agents
ATC classes
Cross-references
Synonyms
- ESTROGENIC SUBSTANCE
- NATURAL ESTROGENIC SUBSTANCE-ESTRONE
- THEELIN
- estron
- estrugenone
- oestrin
- oestrone
- Estrona
- 1,3,5-estratrien-3-ol-17-one
- Estradiol metabolite e1
- Follicular-hormone
- Folliculin
- Folliculinum
- Ketohydroxyestrin
- Thelykinin
- Tokokin
- NSC-9699
- WAY 164397
- Estrogenic substance
- Natural estrogenic substance-estrone
- Theelin
- Aquacrine
- Crinovaryl
- Cristallovar
- Crystogen
- Destrone
- Disynformon
- Endofolliculina
- Esterone
- Estrin
- Estrol
- Estron
- Estronum
- Estrovarin
- Estrugenone
- Estrusol
- Femidyn
Reported adverse events
- Cardiovascular disorder
- Headache
- Nausea
Look up ESTRONE in the interactive SynDRA portal →