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TRIMETAZIDINE
SynDRA canonical compound SYN0006133 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | ACAA2 |
|---|
| Mechanism of action | 3-ketoacyl CoA thiolase inhibitor |
|---|
| Indication | angina pectoris |
|---|
| Disease area | cardiology |
|---|
All known targets
Mechanisms of action (all sources)
- 3-ketoacyl CoA thiolase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- OPRK1
- ACHE
- NPY1R
- MMP1
- MLYCD
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KDM4A
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- GMNN
- GHSR
- MMP9
- NPY2R
- ADORA1
- PTPRC
- TDP1
- TBXAS1
- TBXA2R
- TARDBP
- TACR2
- TACR1
- SMAD3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ABC3A
- ABC3G
- ANDR
- CP1A2
- CTDS1
Drug classes
- Cardiovascular Agents
- Vasodilator Agents
ATC classes
- C01E · OTHER CARDIAC PREPARATIONS
Cross-references
Synonyms
- kyurinett
- vastarel
- trimetazidine hydrochloride
- trimetazidine dihydrochloride
- trimetazidine HCl
- Trimetazidina
- Dilatan
- Vastarel
- Vastarel mr
- Trimetazidine dihydrochloride
- 1-(2,3,4-Trimethoxybenzyl)piperazine dihydrochloride
- Kyurinett
- Trimetazidine hydrochloride
- Trimetajust
- Lubomail
- Yosimilon
- Trimetazidine HCl
- Trimetazidine (dihydrochloride)
- 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine dihydrochloride
- Trimetazidine DiHCl
- UNII-48V6723Z1P
- EINECS 236-117-0
- S 4004
- 48V6723Z1P
- Piperazine, 1-[(2,3,4-trimethoxyphenyl)methyl]-, dihydrochloride
- DSSTox_RID_80858
- DSSTox_CID_25407
- DSSTox_GSID_45407
- W-108326
- Piperazine, 1-(2,3,4-trimethoxyb
- 1-[(2,3,4-trimethoxyphenyl)methyl]piperazine
- Trimetazidinum
- N9A0A0R9S8
- Piperazine, 1-((2,3,4-trimethoxyphenyl)methyl)-
- Piperazine, 1-[(2,3,4-trimethoxyphenyl)methyl]-
- 1-((2,3,4-trimethoxyphenyl)methyl)piperazine
- Vastarel MR
- RefChem:191732
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