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AMIKACIN

SynDRA canonical compound SYN0006026 — structure-anchored drug synonym record

All known targets

• Stap-coc pbp2
• mphB

Mechanisms of action (all sources)

• bacterial 30S ribosomal subunit inhibitor
• Stap-coc pbp2 BINDER

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• ESR1
• ACHE
• MAPK1
• NR1I2
• NPY2R
• NPY1R
• MMP9
• MMP1
• MLNR
• MC5R
• MC4R
• MC3R
• MAPK3
• MAPK14
• MAOA
• HMGCR
• LMNA
• LCK
• KCNH2
• KAT2A
• HTR6
• HTR3A
• HTR2C
• HTR2B
• HTR2A
• HTR1A
• HRH2
• NR3C1
• OPRD1
• OPRK1
• SIGMAR1
• TERT
• TBXAS1
• TBXA2R
• TACR2
• TACR1
• SLCO1B3
• SLCO1B1
• SLC6A4
• SLC6A3

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• ATRX
• CRHBP
• CRHR2
• MLLT3
• RGAP1
• SAE1
• UBA2

Drug classes

• Aminoglycoside Antibacterial
• Anti-Bacterial Agents
• Anti-Infective Agents

ATC classes

• S01A · ANTIINFECTIVES
• D06A · ANTIBIOTICS FOR TOPICAL USE
• J01G · AMINOGLYCOSIDE ANTIBACTERIALS
• COMBINATIONS OF ANTIBACTERIALS

Cross-references

• PubChem CID: 37768
• ChEMBL: CHEMBL177
• DrugBank: DB00479
• ChEBI: CHEBI:2637
• KEGG: D00865
• RxNorm: 641
• PDB: AKN
• Wikipedia: Amikacin
• TTD: D0Y3MO
• LINCS BRD: BRD-K88043978

Synonyms

• AMIKACIN SULFATE
• AMIKACIN SULFATE IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
• AMIKIN
• AMIKIN IN SODIUM CHLORIDE 0.9% IN PLASTIC CONTAINER
• ARIKAYCE KIT
• Arikayce
• amicacin
• amikacillin
• arikace
• lukadin
• amikacin sulfate
• amikacin hydrate
• Amikacine
• Amikacina
• Amikacinum
• Lukadin
• Potentox
• BAY 41-6551
• NSC-177001
• Amicacin
• Amikavet
• Amikin
• Arikace
• Briclin
• Kaminax
• Mikavir
• Amikacin Base
• Amikacin Dihydrate
• ANTIBIOTIC BB-K8
• Amiglyde-V
• Amikacin & Tumor Necrosis Factor
• Amikacin (USP)
• Amikacina [INN-Spanish]
• Amikacine [INN-French]
• Amikacinum [INN-Latin]
• Amikin(Disulfate)
• Antibiotic BB-K 8
• BB-K 8

Reported adverse events

• Rash
• Vomiting
• Nausea
• Pyrexia
• Anxiety
• Bronchitis
• Bronchospasm
• Chest discomfort
• Cough
• Dry mouth
• Dysgeusia
• Dysphonia