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LEVONORGESTREL
SynDRA canonical compound SYN0005965 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | PGR |
|---|
| Mechanism of action | Glucocorticoid receptor antagonist |
|---|
| Indication | contraceptive |
|---|
| Disease area | endocrinology |
|---|
All known targets
- PGR
- ESR1
- AR
- Ar
- CYP2E1
- NR3C1
- SHBG
- SLC6A4
- SRD5A1
Mechanisms of action (all sources)
- ESR1 AGONIST
- PGR AGONIST
- PGR ANTAGONIST
- NR3C1 ANTAGONIST
- PGR BINDER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB11
- HTR2B
- SLC6A3
- SLC6A2
- SAMHD1
- PTGS1
- PDE4A
- PDE3A
- OPRM1
- MAOA
- KDR
- KCNH2
- HTR1A
- ACHE
- HRH3
- HDAC6
- F2
- DRD3
- DRD1
- CHRM2
- CHRM1
- ADRA2A
- ADRA1A
- ADORA3
- TBXA2R
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ANDR
- RARA
- NR1I2
- NR1H4
- NF2L2
- MDR1
- KSYK
- KCMB1
- IFNG
- GLI3
- GCR
- ESRRA
- ESR2
- CP3A7
- CP3A4
- CP2CJ
- CP2C9
- CP19A
- SYK
Drug classes
- Contraceptive Agents
- Contraceptive Agents, Female
- Contraceptive Agents, Hormonal
- Contraceptives, Oral, Hormonal
- Contraceptives, Oral, Synthetic
- Reproductive Control Agents
- Progestin
- Progestin-containing Intrauterine Device
ATC classes
- G03A · HORMONAL CONTRACEPTIVES FOR SYSTEMIC USE
- PROGESTOGENS AND ESTROGENS IN COMBINATION
Cross-references
Synonyms
- AFIRMELLE
- ALESSE
- ALTAVERA
- ASHLYNA
- ATHENTIA NEXT
- AVIANE-21
- AVIANE-28
- AYUNA
- After banger
- AfterPlan
- Aftera
- Afterpill
- 18-Methylnorethindrone
- D-Norgestrel
- dexnorgestrel
- norgestrel
- Norgestrel (-)-form
- Levonorgestrelum
- Norgestrel, (-)-
- BAY86-5028
- NSC-744007
- WY-5104
- Athentia next
- Emerres
- Emerres una
- Ezinelle
- Fallback solo
- Her style
- Isteranda
- Jadelle
- Jaydess
- Levonelle
- Levonelle one step
- Levonelle-2
- Levonorgestrel component of afirmelle
- Levonorgestrel component of alesse
- Levonorgestrel component of altavera
- Levonorgestrel component of aviane
Reported adverse events
- Nausea
- Headache
- Acne
- Budd-Chiari syndrome
- Rash
- Hirsutism
- Erythema nodosum
- Optic neuritis
- Hypertension
- Nervousness
- Erythema multiforme
- Dizziness
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