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DIPHENYLENEIODONIUM
SynDRA canonical compound SYN0005901 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | NOS3 |
|---|
| Mechanism of action | Nitric oxide synthase inhibitor |
|---|
All known targets
- GPR3
- NOS2
- NOS3
- ALDH1A2
- ALDH2
- ALDH5A1
- ALDH7A1
- NOX3
- XDH
Mechanisms of action (all sources)
- Nitric oxide synthase inhibitor
- GPR3 FULL AGONIST
- GPR3 AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- CYBB
- NOX5
- NOX4
- NOX1
- ALDH1A1
- MAPK1
- TP53
- THPO
- TDP1
- STAT6
- SMN1
- RGS4
- NPC1
- NFE2L2
- MTOR
- HDAC6
- ALOX15B
- GPR6
- GPR12
- FEN1
- EHMT2
- CYP3A4
- CYP2D6
- CYP2C9
- CYP2C19
- CYP1A2
- ATXN2
- ATAD5
- TSHR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ADCY9
- CP1A2
- TPO
- STK33
- NTM1A
- NPR2
- NPR1
- MDR1
- MAPT
- IFNG
- IFNB1
- HLAB
- GPR32
- GEMI
- ESRRA
- CP3A4
- CP2D6
- CP2CJ
- CP2C9
- YAP1
Drug classes
- Enzyme Inhibitors
- Hypoglycemic Agents
Cross-references
Synonyms
- Dibenziodolium
- Diphenylene iodonium
- 2,2'-Biphenylyleneiodonium
- dibenzo[b,d]iodolium
- (1,1'-Biphenyl)-2,2'-diyliodonium
- Dibenzo[b,d]iodol-5-ium
- diphenyl-iodonium hydrochloride
- CHEBI:77986
- 6HJ411TU98
- 8-iodoniatricyclo[7.4.0.02,7]trideca-1(13),2,4,6,9,11-hexaene
- CHEMBL397686
- UNII-6HJ411TU98
- Tocris-0504
- Lopac-D-2926
- Lopac0_000367
- BSPBio_001027
- KBioGR_000367
- KBioSS_000367
- SCHEMBL219548
- CHEMBL365739
- KBio2_000367
- KBio2_002935
- KBio2_005503
- KBio3_000713
- KBio3_000714
- QFXKXRXFBRLLPQ-UHFFFAOYSA-
- DTXSID00924595
- Bio1_000428
- Bio1_000917
- Bio1_001406
- Bio2_000344
- Bio2_000824
- HMS1362C09
- HMS1792C09
- HMS1990C09
- HMS3403C09
- BDBM50206334
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