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THIETHYLPERAZINE
SynDRA canonical compound SYN0005862 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | DRD1 | DRD2 | DRD4 |
|---|
| Mechanism of action | dopamine receptor antagonist |
|---|
| Indication | nausea |
|---|
| Disease area | gastroenterology |
|---|
All known targets
- DRD2
- DRD1
- ADRA1A
- GFER
- PDR5
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH1
- DRD4
- CHRM1
Mechanisms of action (all sources)
- DRD2 ANTAGONIST
- Dopamine D2 receptor antagonist
- dopamine receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- ADORA3
- ADRA2A
- ADRA2C
- TBXA2R
- SLC6A4
- SLC6A3
- SLC6A2
- OPRM1
- PGR
- MAOA
- MC3R
- NR1I2
- PDE3A
- PDE4A
- PDE4D
- RAD52
- PLIN1
- POLK
- PTGS1
- KDR
- SAMHD1
- SMAD3
- TDP1
- LMNA
- ACHE
- KDM4A
- ADORA2A
- ADRB1
- AR
- ATAD5
- BAZ2B
- CBX1
- CHRNA4
- CYP1A2
- CYP2C19
- CYP2C9
- CYP2D6
- CYP3A4
- EHMT2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ALR
- APAF
- CP1A2
- CP2D6
- IDHC
- IFNG
- IL1B
- MAPT
- MDM2
- MDM4
- MLLT3
- NTR1
- PAFA
- PLIN5
Drug classes
- Antiemetics
- Central Nervous System Agents
- Dopamine Agents
- Dopamine Antagonists
- Gastrointestinal Agents
- Neurotransmitter Agents
- Peripheral Nervous System Agents
ATC classes
- R06A · ANTIHISTAMINES FOR SYSTEMIC USE
Cross-references
Synonyms
- TORECAN
- ethylthioperazine
- thiethylperazine malate
- thiethylperazine maleate
- thiethylperazine dimalate
- Tietilperazina
- ETHYLTHIOPERAZINE
- Theithylperazine
- Thiethylperazinum
- Thiethylpipezazine
- Thioethylperazine
- Torecan
- Tietilperazina [DCIT]
- Thiethylperazinum [INN-Latin]
- Torecan (TN)
- Thiethylperazine (USAN/INN)
- Thiethylperazine [USAN:INN:BAN]
- Norzine (*Dimaleate*)
- GS-95 (*Dimaleate*)
- 8ETK1WAF6R
- CHEBI:9544
- RefChem:897744
- DTXCID403651
- R06AD03
- MLS002154140
- HSDB 3400
- C22H29N3S2
- SMR001233447
- EINECS 215-819-0
- UNII-8ETK1WAF6R
- MFCD00865537
- Norzine (Salt/Mix)
- Torecan (Salt/Mix)
- Tresten (Salt/Mix)
- SCHEMBL49124
- THIETHYLPERAZINE [MI]
- THIETHYLPERAZINE [INN]
- THIETHYLPERAZINE [HSDB]
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