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MODAFINIL
SynDRA canonical compound SYN0005807 — structure-anchored drug synonym record
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SLC6A3 |
|---|
| Mechanism of action | Adrenergic receptor agonist |
|---|
All known targets
- SLC6A3
- ADRA1B
- CYP1A2
- CYP2C19
- DRD2
- DRD3
- NET
- Slc6a3
- Slc6a4
Mechanisms of action (all sources)
- Adrenergic receptor agonist
- SLC6A3 INHIBITOR
- Dopamine transporter inhibitor
- SLC6A3 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- HTR6
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KCNH2
- HTR7
- HTR5A
- MMP9
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- GMNN
- GIPR
- MMP1
- NPY1R
- GCGR
- PTGS1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLCO1B3
- SLCO1B1
- SLC6A2
- SLC29A1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Central Nervous System Agents
- Central Nervous System Stimulants
- Cytochrome P-450 CYP3A Inducers
- Metabolic Side Effects of Drugs and Substances
- Wakefulness-Promoting Agents
- Sympathomimetic-like Agent
- Adrenergic Agents
- Adrenergic Agonists
- Adrenergic alpha-Agonists
- Neurotransmitter Agents
ATC classes
- N06B · PSYCHOSTIMULANTS, AGENTS USED FOR ADHD AND NOOTROPICS
Cross-references
Synonyms
- PROVIGIL
- Provigil
- (+/-)-Modafinil
- modaphonil
- modiodal
- Modafinilo
- Modaphonil
- Modiodal
- CEP-1538
- CRC-40476
- CRL-40476
- DEP-1538
- MODAFINIL COMPONENT OF THN-102
- MODAFINIL COMPONENT OF THN102
- NSC-751178
- NSC-759110
- Modafinil civ
- 2-((Diphenylmethyl)sulfinyl)acetamide
- Acetamide, 2-((diphenylmethyl)sulfinyl)-
- NSC 751178
- modafinil civ (usp-rs)
- THN102 COMPONENT MODAFINIL
- modafinil (ep monograph)
- NSC 759110
- THN-102 COMPONENT MODAFINIL
- (+-)-Modafinil
- R3UK8X3U3D
- modafinil (usp monograph)
- 2-(Benzhydrylsulfinyl)acetamide
- 2-[(diphenylmethyl)sulfinyl]acetamide
- 2 Benzhydrylsulfinylacetamide
- Modafinilum
- R Modafinil
- DTXCID103329
- CHEBI:77585
- 2-(diphenylmethane)sulfinylacetamide
- 2-(di(phenyl)methylsulfinyl)acetamide
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