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METHYLENE BLUE CATION
SynDRA canonical compound SYN0005792 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ACHE |
|---|
| Mechanism of action | Nitric oxide production inhibitor |
|---|
| Indication | methemoglobinemia |
|---|
| Disease area | hematology |
|---|
All known targets
- ACHE
- MAPT
- APP
- GR3
- GSR
- GUCY1A1
- GUCY1A2
- GUCY1B1
- MAOA
- MAOB
- TXNRD1
Mechanisms of action (all sources)
- Tau aggregation inhibitor
- Guanylyl cyclase inhibitor
- Monoamine oxidase inhibitor
- Nitric oxide production inhibitor
- GUCY1B1 INHIBITOR
- GUCY1A2 INHIBITOR
- GUCY1A1 INHIBITOR
- ACHE INHIBITOR
- MAPT INHIBITOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- TST
- ALDH1A1
- PTH1R
- MSTN
- NFE2L2
- NPSR1
- NR1H4
- NR3C1
- PIN1
- PKM
- POLB
- POLH
- POLI
- POLK
- PPARD
- PPARG
- PTPN1
- ALOX15
- RAD52
- RECQL
- RORC
- SMAD3
- SMN1
- SNCA
- TARDBP
- TDP1
- THRB
- TNF
- TP53
- TSHR
- MBNL1
- MAPK1
- LHCGR
- KMT2A
- APAF1
- APEX1
- ATAD5
- ATM
- ATXN2
- BAZ2B
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- A4
- KSYK
- MBD2
- MCL1
- MDM2
- MDM4
- MEN1
- MITF
- MLLT3
- NCF1
- NCOA1
- NCOA3
- NF2L2
- NR1I2
- NR5A2
- NSD2
- NTM1A
- NTMT1
- PE2R2
- PSIP1
- RARA
- RGS4
- RXFP1
- SENP8
- SIX1
- STAT1
- SYK
- TCPB
- THB
- TNF10
- TR10B
- LARG1
- JUN
- ACES
- JAK2
- AHR
- ALR
- ANDR
- APAF
- APLNR
Drug classes
ATC classes
- V04C · OTHER DIAGNOSTIC AGENTS
- V03A · ALL OTHER THERAPEUTIC PRODUCTS
Cross-references
Synonyms
- METHYLENE BLUE
- PROVAYBLUE
- Provayblue
- methylthioninium chloride
- methylthioninium benzalkonium chloride hydrate
- methylthioninium chloride hydrate
- methylenum coeruleum
- methylthioninium chloratum
- methylene blue
- aizen methylene blue
- proveblue
- Dndi1417128
- 3,7-BIS(DIMETHYLAMINO)PHENOTHIAZIN-5-IUM
- UNII-ZMZ79891ZH
- N-[7-(dimethylamino)-3H-phenothiazin-3-ylidene]-N-methylmethanaminium
- ZMZ79891ZH
- CHEBI:43830
- azul de metileno
- Methylthionine HCl
- Methylthionine chloride
- CHEMBL405110
- NSC3089
- NSC617593
- NSC215213
- NCGC00167496-03
- NCGC00167496-01
- C.I. 52015
- Methylthioninium
- Methylene Blue parent
- AI3-52463
- cid_6099
- AC1Q4UZ6
- AC1L1HI1
- SCHEMBL109755
- CHEMBL191083
- DTXSID3047009
- NOCAS_47009
- RBTBFTRPCNLSDE-UHFFFAOYSA-N
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