← SynDRA

BUFLOMEDIL

SynDRA canonical compound SYN0005785 — structure-anchored drug synonym record

All known targets

• ADRA1A
• ADRA1B
• ADRA1D
• ADRA2A
• ADRA2C
• CACNA1C
• CACNG1
• EBP
• ERG2
• SIGMAR1

Mechanisms of action (all sources)

• Calcium channel blocker
• Adrenergic receptor antagonist

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• OPRK1
• KCNH2
• ACHE
• MAOA
• NPY1R
• MMP9
• MMP1
• MLNR
• MC5R
• MC4R
• MC3R
• MAPK3
• MAPK14
• MAPK1
• LMNA
• NR1I2
• LCK
• HTR6
• HTR3A
• HTR2C
• HTR2B
• HTR2A
• HTR1A
• HRH3
• HRH2
• HRH1
• NPY2R
• NR3C1
• ADORA1
• OPRD1
• TTR
• THRB
• TDP1
• TBXAS1
• TBXA2R
• TACR2
• TACR1
• SLC6A4
• SLC6A3
• SLC6A2

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• CP2D6
• MDR1

Drug classes

• Cardiovascular Agents
• Vasodilator Agents

ATC classes

• C04A · PERIPHERAL VASODILATORS

Cross-references

• PubChem CID: 2467
• ChEMBL: CHEMBL188921
• DrugBank: DB13510
• ChEBI: CHEBI:94538
• KEGG: D07176
• RxNorm: 19836
• Wikipedia: Buflomedil
• TTD: D0Z6ST
• LINCS BRD: BRD-K19462402

Synonyms

• buflomedil hydrochloride
• buflomedil HCl
• Loftyl
• Buflomedil hydrochloride
• Buflomedilum
• 4-(1-Pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-1-butanone
• V7I71DQ432
• 4-(pyrrolidin-1-yl)-1-(2,4,6-trimethoxyphenyl)butan-1-one
• blufomedil
• bufomedil
• RefChem:121854
• DTXCID902697
• C04AX20
• 2,4,6-trimethoxyphenyl-3-pyrrolidine propyl ketone
• 1-Butanone, 4-(1-pyrrolidinyl)-1-(2,4,6-trimethoxyphenyl)-
• 4-pyrrolidin-1-yl-1-(2,4,6-trimethoxyphenyl)butan-1-one
• 2',4',6'-Trimethoxy-4-(1-pyrrolidinyl)butyrophenone
• Buflomedil (INN)
• BUFLOMEDIL [INN]
• Buflomedilum [INN-Latin]
• Buflomedil [INN:BAN:DCF]
• NCGC00016831-01
• EINECS 259-851-3
• CAS-35543-24-9
• UNII-V7I71DQ432
• BUFLOMEDIL [MI]
• Prestwick0_000426
• Prestwick1_000426
• Prestwick2_000426
• Prestwick3_000426
• BUFLOMEDIL [WHO-DD]
• BSPBio_000412
• SCHEMBL150905
• SPBio_002351
• BPBio1_000454
• orb1710724
• CHEBI:94538
• HY-B0484A