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OPIPRAMOL
SynDRA canonical compound SYN0005775 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Mechanism of action | sigma receptor agonist |
|---|
| Indication | generalized anxiety disorder (GAD) |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR1A
- CHRM2
- DRD1
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- HRH1
- KCNH2
- DRD2
- SLC6A2
- DRD3
- NR1I2
- NFKB1
- NPY1R
- MAPK1
- MPHOSPH8
- MLNR
- MC3R
- OPRD1
- MAOA
- HTR3A
- HTR2C
- NR3C1
- ACHE
- OPRK1
- OPRM1
- TRPV1
- TDP1
- TBXA2R
- SLC6A4
- SLC6A3
- SLC29A1
- SAMHD1
- PTGS2
- PTGS1
- PPARG
- PMP22
- PGR
- PDE4D
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Adrenergic Agents
- Adrenergic Uptake Inhibitors
- Antidepressive Agents
- Antidepressive Agents, Tricyclic
- Central Nervous System Agents
- Membrane Transport Modulators
- Neurotransmitter Agents
- Neurotransmitter Uptake Inhibitors
- Psychotropic Drugs
ATC classes
Cross-references
Synonyms
- opipramol dihydrochloride
- opramidol
- Opipramol dura
- NSC-169867
- Opipramolo
- Opipramolum
- Opipramol dihydrochloride
- Opipramol hydrochloride
- Opipramoli hydrochloridum
- G 33 040
- NSC 169867
- D23ZXO613C
- 4-(3-(5H-Dibenz(b,f)azepin-5-yl)propyl)-1-piperazineethanol
- 4-[3-(5H-Dibenz[b,f]azepin-5-yl)propyl]-1-piperazineethanol
- RefChem:168394
- DTXCID203394
- N06AA05
- Nisidana
- Opipramol G
- Opramidol
- Endison
- Insidon, base
- Insidon (free base)
- Pramolan (free base)
- Opipramol (INN)
- MFCD00865455
- N-(3-(4-(2-Hydroxyethyl)piperazino)propyl)iminostilbene
- N-[3-[4-(2-Hydroxyethyl)piperazino]propyl]iminostilbene
- GR 33040
- OPIPRAMOL [INN]
- G-33040
- Opipramol [INN:BAN]
- Opipramolum [INN-Latin]
- NCGC00162068-04
- EINECS 206-254-0
- BRN 0627076
- UNII-D23ZXO613C
- Insidon (Salt/Mix)
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