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BUNAZOSIN
SynDRA canonical compound SYN0005766 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | ADRA1A |
|---|
| Mechanism of action | adrenergic receptor antagonist |
|---|
| Indication | glaucoma | intraocular pressure |
|---|
| Disease area | ophthalmology |
|---|
All known targets
- ADRA1A
- ADRA1B
- ADRA1D
- ADRA2B
- NQO2
Mechanisms of action (all sources)
- ADRA1A ANTAGONIST
- Adrenergic receptor alpha-1 antagonist
- ADRA1D ANTAGONIST
- ADRA1B ANTAGONIST
- adrenergic receptor antagonist
- ADRA1D MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA2C
- KCNH2
- ADORA1
- NR3C1
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- MAOA
- MC3R
- MLNR
- NPY1R
- NR1I2
- OPRD1
- HRH3
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PPARG
- PTGS2
- SLC29A1
- SLC6A2
- SLC6A3
- HTR1A
- HRH2
- ADORA2A
- CHRM1
- ADORA3
- ADRA2A
- ADRB1
- ADRB2
- AGTR1
- AVPR1A
- AVPR2
- BDKRB2
- CCKAR
- CCKBR
- CHRM2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Adrenergic Agents
- Adrenergic alpha-1 Receptor Antagonists
- Adrenergic alpha-Antagonists
- Adrenergic Antagonists
- Neurotransmitter Agents
Cross-references
Synonyms
- bunazosin hydrochloride
- detantol
- bunazosin HCl
- Bunazosine
- Bunazosina
- Andante
- E 015
- DE-070
- Detantol-R
- E-1015
- E-643
- Bunazosinum
- 9UUW4V7G2H
- bunazocine
- RefChem:121901
- DTXCID602700
- Bunazosin [INN]
- Bunazosin (INN)
- Bunazosine [French]
- Bunazosinum [Latin]
- Bunazosina [Spanish]
- SR-01000945226
- NCGC00183272-01
- UNII-9UUW4V7G2H
- C19H27N5O3
- BUNAZOSIN [MI]
- BUNAZOSIN [WHO-DD]
- SCHEMBL49348
- MLS006011493
- orb1685215
- SCHEMBL29456750
- SCHEMBL29750637
- CHEBI:135576
- BDBM50088386
- EBC-14148
- MFCD00865793
- AKOS030228613
- AS-73224
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