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CHLORZOXAZONE
SynDRA canonical compound SYN0005754 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | KCNN4 |
|---|
| Mechanism of action | Bacterial 30S ribosomal subunit inhibitor |
|---|
| Indication | muscle relaxant |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- KCNN4
- KCNMA1
- Kcnn2
- NOS1
- NOS2
- NOS3
- Nos1
Mechanisms of action (all sources)
- Bacterial 30S ribosomal subunit inhibitor
- KCNN4 OPENER
- Intermediate conductance calcium-activated potassium channel protein 4 opener
- KCNN4 AGONIST
- KCNMA1 OPENER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ADRA2A
- DRD2
- MC5R
- MAPK14
- MAPK3
- MBNL1
- MC3R
- MC4R
- ABCB1
- MAOA
- MLNR
- MMP1
- MMP9
- NPSR1
- NPY1R
- NPY2R
- MAPK1
- LMNA
- NR3C1
- LCK
- KCNH2
- KAT2A
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH2
- HRH1
- HMGCR
- NR1I2
- OPRD1
- GMNN
- SLC22A1
- TSHR
- THPO
- TBXAS1
- TBXA2R
- TACR2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Central Nervous System Agents
- Muscle Relaxants, Central
- Neuromuscular Agents
- Peripheral Nervous System Agents
- Muscle Relaxant
ATC classes
- M03B · MUSCLE RELAXANTS, CENTRALLY ACTING AGENTS
Cross-references
Synonyms
- Lorzone
- PARAFLEX
- PARAFON FORTE DSC
- STRIFON FORTE DSC
- 5-Chlorobenzoxazolidone
- chlorzoxazon
- chloroxazone
- Clorzoxazona
- NSC-26189
- Paraflex
- Parafon
- Parafon forte dsc
- Parafon-forte
- Strifon
- Strifon forte dsc
- Biomioran
- CLW
- Chloroxazone
- Chlorsoxazone
- Chlorzoxane
- Chlorzoxazon
- Chlorzoxazona
- Chlorzoxazonum
- Escoflex
- Klorzoxazon
- Mioran
- Miotran
- Myoflexin
- Myoflexine
- Neoflex
- Nyoflex
- Pathorysin
- Relaxazone
- Remofleks
- Remular
- Solaxin
- Component of Parafon Forte
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