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BUDESONIDE
SynDRA canonical compound SYN0005731 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | NR3C1 |
|---|
| Mechanism of action | Glucocorticoid receptor agonist |
|---|
| Indication | Crohn's disease |
|---|
| Disease area | gastroenterology |
|---|
All known targets
- NR3C1
- ABCB1
- Ar
- CYP3A5
- CYP3A7
- IFNG
- IL5
- Il5
- Il5ra
- MMP9
- NR3C2
- Nr3c1
Mechanisms of action (all sources)
- NR3C1 AGONIST
- NR3C1 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- ESR2
- ESR1
- MC3R
- KDR
- LCK
- MAOA
- MAPK1
- MAPK14
- MAPK3
- MC4R
- HTR6
- MC5R
- MLNR
- MMP1
- MTOR
- NFKB1
- KCNH2
- ABCB11
- HTR3A
- NPY1R
- HTR2B
- HTR2A
- HTR1A
- HSD17B10
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- GSK3B
- GMNN
- GLP1R
- GHSR
- HTR2C
- NPY2R
- FYN
- SULT2A1
- SLC6A3
- SLC6A4
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- AHR
- KCMB2
- TLR3
- T22D3
- STAT1
- RARA
- PRGR
- NF2L2
- MDR1
- MCR
- M3K3
- KCMB1
- ANDR
- KCMA1
- JUN
- IL1B
- GLI3
- ESRRA
- CP3A4
- CP2CJ
- CP2C9
- CFTR
- TRFR
Drug classes
- Corticosteroid Hormone Receptor Agonists
- Corticosteroid
- Anti-Asthmatic Agents
- Anti-Inflammatory Agents
- Bronchodilator Agents
- Glucocorticoids
- Hormones
- Peripheral Nervous System Agents
- Respiratory System Agents
ATC classes
- A07E · INTESTINAL ANTIINFLAMMATORY AGENTS
- R03B · OTHER DRUGS FOR OBSTRUCTIVE AIRWAY DISEASES, INHALANTS
- D07A · CORTICOSTEROIDS, PLAIN
- R01A · DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
- ADRENERGICS, INHALANTS
Cross-references
Synonyms
- AIRSUPRA
- BREYNA
- BREZTRI AEROSPHERE
- BUDESONIDE AND FORMOTEROL FUMARATE DIHYDRATE
- ENTOCORT EC
- EOHILIA
- Entocort
- Eohilia
- ORTIKOS
- Ortikos
- PULMICORT
- barazone
- budesomide
- budeson
- Budesonida
- MAP-0010
- MAP0010
- NSC-757788
- R01AD05
- S-1320
- Aircort
- Budeflam aquanase
- Budelin novolizer
- Budenofalk
- Budesonide component of airsupra
- Budesonide component of breztri
- Budesonide component of symbicort
- Budesonide component of uceris
- Cortiment
- Duoresp spiromax
- Entocort cr
- Entocort ec
- Jorveza
- Kinpeygo
- Preferid
- Pulmaxan
- Pulmicort flexhaler
Reported adverse events
- Infection
- Vomiting
- Bronchospasm
- Immunosuppression
- Cataract
- Cough
- Hypersensitivity
- Glaucoma
- Rash
- Epistaxis
- Infestation
- Conjunctivitis
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