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VILAZODONE
SynDRA canonical compound SYN0005716 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SLC6A4 |
|---|
| Mechanism of action | Serotonin reuptake inhibitor |
|---|
| Indication | depression |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- SLC6A4
- HTR1A
- HTR4
- DRD3
- HRH1
- DRD2
- Htr6
- Htr4
- Htr3b
- Htr1a
- Htr7
- Htr3a
Mechanisms of action (all sources)
- Serotonin reuptake inhibitor
- SLC6A4 INHIBITOR
- Serotonin transporter inhibitor
- HTR1A PARTIAL AGONIST
- Serotonin 1a (5-HT1a) receptor partial agonist
- HTR4 AGONIST
- DRD2 AGONIST
- DRD3 AGONIST
- HRH1 AGONIST
- SLC6A4 MODULATOR
- HTR1A MODULATOR
- HTR1A AGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- GPR183
- KCNH2
- ADRB2
- TMEM97
- FPR3
- SIGMAR1
- OPRM1
- HTR2B
- HDAC6
- HRH3
- HRH4
- HTR1E
- HTR5A
- ADGRF1
- NEIL1
- OGG1
- GPR35
- OPRK1
- S1PR1
- SMUG1
- TDG
- TSPO
- OPRD1
- GPR119
- ADRB1
- CHRM5
- AGTR1
- APLNR
- C5AR1
- CHRM1
- CHRM2
- CHRM3
- CHRM4
- CX3CR1
- GLP1R
- CYP1A2
- CYP2C9
- CYP3A4
- DRD1
- DRD5
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT4R
- ADCY9
- COMT
- CP2C9
- CP2D6
- CP3A7
- GAMT
- GNMT
- HNMT
- KSYK
- NNMT
- NSD2
- PNMT
- SYK
Drug classes
- Antidepressive Agents
- Central Nervous System Agents
- Membrane Transport Modulators
- Neurotransmitter Agents
- Neurotransmitter Uptake Inhibitors
- Psychotropic Drugs
- Selective Serotonin Reuptake Inhibitors
- Serotonin 5-HT1 Receptor Agonists
- Serotonin Agents
- Serotonin Receptor Agonists
ATC classes
Cross-references
Synonyms
- VIIBRYD
- VILAZODONE HYDROCHLORIDE
- Viibryd
- viibryd
- vilazodone hydrochloride
- vilazodone HCl
- Vilazodona
- EMD 68843 BASE
- EMD-515259
- EMD 68 843
- Vilazodone [INN]
- Vilazodone (TN)
- S239O2OOV3
- EMD-68843 BASE
- vilazodona
- vilazodonum
- CHEBI:70707
- RefChem:56210
- DTXCID10817924
- N06AX24
- MFCD09838919
- EMD 68843 (Hydrochloride);SB659746A (Hydrochloride)
- Vilazodone [USAN:INN]
- UNII-S239O2OOV3
- HSDB 8197
- YG7
- Vilazodone (Standard)
- VILAZODONE [MI]
- Vilazodone (USAN/INN)
- VILAZODONE [USAN]
- VILAZODONE [VANDF]
- VILAZODONE [MART.]
- VILAZODONE [WHO-DD]
- SCHEMBL650682
- GTPL7427
- orb1309142
- SCHEMBL29357448
- SCHEMBL30051446
Reported adverse events
- Abnormal dreams
- Arthralgia
- Dizziness
- Dry mouth
- Dyspepsia
- Ejaculation disorder
- Fatigue
- Flatulence
- Gastroenteritis
- Headache
- Hypomania
- Insomnia
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