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NIFEKALANT
SynDRA canonical compound SYN0005660 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Mechanism of action | potassium channel blocker |
|---|
| Indication | ventricular arrhythmias | ventricular tachycardia (VT) |
|---|
| Disease area | cardiology |
|---|
All known targets
- KCNH2
- SLC22A2
- SLC47A1
- SLC47A2
Mechanisms of action (all sources)
- potassium channel blocker
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABL1
- NR1I2
- HDAC6
- HRH1
- HRH2
- HRH3
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- MAOA
- MAPK1
- MC3R
- MLNR
- NPY1R
- NR3C1
- GMNN
- OPRD1
- OPRK1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PTGS2
- PTH1R
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- TBXA2R
- TRIM24
- GSK3B
- GHSR
- ADORA1
- BRPF1
- ADORA2A
- ADORA3
- ADRA1A
- ADRA2A
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anti-Arrhythmia Agents
- Cardiovascular Agents
Cross-references
Synonyms
- Nifekalant hydrochloride
- 5VZ7GZM43E
- nifekalantum
- RefChem:165783
- DTXCID3028348
- Nifekalant [INN]
- NIFEKALANT HYDROCHLORIDE [JAN]
- NCGC00164637-01
- UNII-5VZ7GZM43E
- NIFEKALANT [MI]
- NIFEKALANT [WHO-DD]
- SCHEMBL157527
- orb2663978
- CHEBI:94575
- OEBPANQZQGQPHF-UHFFFAOYSA-N
- HMS2090C07
- HMS3715M05
- HY-B0772
- BDBM50151866
- AKOS022180678
- CCG-221022
- NCGC00164637-04
- DB-041977
- NS00125152
- H41418
- T89560
- AB00698502-07
- AB00698502-09
- SR-01000763409
- SR-01000763409-3
- BRD-K32311154-001-01-0
- MLS000759497
- CHEBI:31909
- N3422
- Nifekalant hydrochloride, >=98% (HPLC)
- nifekalant hydrochloride
- FN65104
- AC-3499
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