← SynDRA

TALTOBULIN

SynDRA canonical compound SYN0005628 — structure-anchored drug synonym record

Mechanisms of action (all sources)

• tubulin polymerization inhibitor

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• TUBB1
• HDAC6

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• IFNG

Cross-references

• PubChem CID: 6918637
• ChEMBL: CHEMBL182319
• DrugBank: DB20832
• KEGG: D06001
• TTD: D09FZI

Synonyms

• Taltobuline
• Taltobulina
• HTI-286
• SPA-110 (trifluoroacetate salt)
• N,3,3-Trimethyl-L-phenylalanyl-N1-[3-carboxy-1(S)-isopropyl-2(E)-butenyl]-N1,3-dimethyl-L-valinamide
• HTI 286
• SPA-110
• CHEMBL182319
• J6D6912BXS
• (E,4S)-4-[[(2S)-3,3-dimethyl-2-[[(2S)-3-methyl-2-(methylamino)-3-phenylbutanoyl]amino]butanoyl]-methylamino]-2,5-dimethylhex-2-enoic acid
• (S,E)-2,5-dimethyl-4-((S)-N,3,3-trimethyl-2-((S)-3-methyl-2-(methylamino)-3-phenylbutanamido)butanamido)hex-2-enoic acid
• UNII-J6D6912BXS
• (4S)-4-(((2S)-3,3-Dimethyl-2-(((2S)-3-methyl-2-(methylamino)-3-phenylbutanoyl)amino)butanoyl)methylamino)-2,5-dimethylhex-2-enoic acid
• (4S)-4-[[(2S)-3,3-Dimethyl-2-[[(2S)-3-methyl-2-(methylamino)-3-phenylbutanoyl]amino]butanoyl]methylamino]-2,5-dimethylhex-2-enoic acid
• PHENYLHEMIASTERLIN
• TALTOBULIN [INN]
• Taltobulin (USAN/INN)
• Taltobulin [USAN:INN]
• TALTOBULIN [USAN]
• SCHEMBL57122
• SCHEMBL4378011
• DTXSID2041040
• ZINC3966291
• BDBM50150589
• CS-3299
• NCGC00386600-02
• HY-15584
• D06001
• E98768
• 266T408
• A911116
• Q27281267
• HTI-286;SPA-110;HTI286;SPA110;HTI 286;SPA 110
• (E)-(S)-4-{[(S)-3,3-Dimethyl-2-((S)-3-methyl-2-methylamino-3-phenyl-butyrylamino)-butyryl]-methyl-amino}-2,5-dimethyl-hex-2-enoic acid
• (S)-2,5-dimethyl-4-((S)-N,3,3-trimethyl-2-((S)-3-methyl-2-(methylamino)-3-phenylbutanamido)butanamido)hex-2-enoic acid
• (S,E)-4-(((S)-3,3-dimethyl-1-((S)-3-methyl-2-(methylamino)-3-phenylbutanamido)-1-oxobutan-2-yl)(methyl)amino)-2,5-dimethylhex-2-enoic acid
• 4-{[3,3-Dimethyl-2-(3-methyl-2-methylamino-3-phenyl-butyrylamino)-butyryl]-methyl-amino}-2,5-dimethyl-hex-2-enoic acid
• L-Valinamide, N,beta,beta-trimethyl-L-phenylalanine-N-((1S,2E)-3-carboxy-1-(1-methylethyl)-2-butenyl)-N,3-dimethyl-