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ARCTIGENIN
SynDRA canonical compound SYN0005472 — structure-anchored drug synonym record
| Clinical phase | Preclinical |
|---|
| Primary target(s) | MAP2K1 |
|---|
| Mechanism of action | MEK inhibitor |
|---|
All known targets
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- APP
- PRKAA2
- MAPK6
- NEK2
- NEK6
- OXSR1
- PAK4
- PAK5
- PAK6
- PBK
- PDPK1
- PIM1
- PIM2
- PIM3
- PLK1
- PLK4
- PRKACA
- MAPK11
- RIOK2
- RPS6KA3
- SLK
- STK10
- STK16
- STK17A
- STK25
- STK26
- STK38
- STK4
- TDP1
- TNIK
- VRK1
- VRK2
- MAPK3
- MAPK1
- CAMK1D
- CLK3
- CAMK1G
- CAMK2A
- CAMK2B
- CAMK2D
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ADCY9
- CP1A2
- CP2C9
- CP3A4
- KSYK
- PDE4B
- SYK
Cross-references
Synonyms
- (-)-Arctigenin
- (+/-)-Arctigenin
- Arctigenin, (+/-)-
- Arctigenin, trans-((+/-)-
- C21H24O6
- (3R,4R)-4-(3,4-dimethoxybenzyl)-3-(4-hydroxy-3-methoxybenzyl)dihydrofuran-2(3H)-one
- CHEBI:79
- U76MR9VS6M
- 2(3H)-Furanone, 4-((3,4-dimethoxyphenyl)methyl)dihydro-3-((4-hydroxy-3-methoxyphenyl)methyl)-, (3R-trans)-
- 2FD8L150E7
- (3R,4R)-4-[(3,4-dimethoxyphenyl)methyl]-3-[(4-hydroxy-3-methoxyphenyl)methyl]oxolan-2-one
- 2(3H)-Furanone, 4-((3,4-dimethoxyphenyl)methyl)dihydro-3-((4-hydroxy-3-methoxyphenyl)methyl)-, (3R,4R)-
- (3R,4R)-4-[(3,4-Dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-2(3H)-furanone
- 2(3H)-Furanone, 4-((3,4-dimethoxyphenyl)methyl)dihydro-3-((4-hydroxy-3-methoxyphenyl)methyl)-, (3R,4R)-rel-
- 2(3H)-Furanone, 4-((3,4-dimethoxyphenyl)methyl)dihydro-3-((4-hydroxy-3-methoxyphenyl)methyl)-, trans-
- (3R,4R)-4-[(3,4-dimethoxyphenyl)methyl]-3- [(4-hydroxy-3-methoxyphenyl)methyl]-2-tetrahydrofuranone
- UNII-U76MR9VS6M
- Arctigenen
- UNII-2FD8L150E7
- 2(3H)-Furanone, 4-[(3,4-dimethoxyphenyl)methyl]dihydro-3-[(4-hydroxy-3-methoxyphenyl)methyl]-, (3R,4R)-
- Tocris-1777
- ARCTIGENIN [INCI]
- ARCTIGENIN, (-)-
- SCHEMBL381820
- CHEMBL435734
- MEGxp0_001799
- ACon1_000416
- ARCTIGENIN, TRANS-(-)-
- DTXSID60998919
- HMS3268E18
- HMS3412H04
- HMS3676H04
- HY-N0035
- ZINC1615344
- BDBM50375656
- HB0119
- MFCD00870597
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