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PHENFORMIN
SynDRA canonical compound SYN0005394 — structure-anchored drug synonym record
| Clinical phase | Withdrawn |
|---|
| Primary target(s) | KCNJ8 | PRKAA1 |
|---|
| Mechanism of action | AMPK activator |
|---|
All known targets
- PRKAA1
- PRKAB1
- KCNJ8
- PRKAG1
Mechanisms of action (all sources)
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR2B
- ADRA2A
- SLC22A1
- ESR1
- ABCC2
- MC4R
- OPRK1
- OPRD1
- NTSR1
- NR3C1
- NPY2R
- NPY1R
- NFE2L2
- MLNR
- MAPT
- MC3R
- PDE3A
- MAOA
- LMNA
- KCNH2
- IDH1
- HTR3A
- HTR2C
- HTR2A
- OPRM1
- PGR
- PDE4D
- SLC6A3
- TSHR
- THRB
- TDP1
- TBXA2R
- SMN1
- SLCO2B1
- SLCO1B3
- SLCO1B1
- SLC6A4
- SLC6A2
- HRH3
- SLC47A2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP2D6
- ESRRA
- KSYK
- MDR1
- NF2L2
- SYK
Drug classes
ATC classes
- A10B · BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Cross-references
Synonyms
- phenformin hydrochloride
- phenformin HCl
- Phenformine
- Fenformina
- Azucaps
- Cronoformin
- DBI
- Debeone
- Debinyl
- Diabis
- Dibein
- Dibiraf
- Dibotin
- Dipar
- Feguanide
- Fenfoduron
- Fenformin
- Fenormin
- Glukopostin
- Glyphen
- Insoral
- Lentobetic
- Meltrol
- Normoglucina
- Pedg
- Phenethyldiguanide
- Phenforminum
- Phenformix
- Phenylethylbiguanide
- Retardo
- D Bretard
- DB Comb
- DBI monohydrochloride
- Phenformine HCl
- Phenoformine hydrochloride
- W 32
- Beta-PEBG
- Beta-Phenethybiguanide
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