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TOMELUKAST
SynDRA canonical compound SYN0005268 — structure-anchored drug synonym record
| Clinical phase | Phase 3 |
|---|
| Primary target(s) | CYSLTR1 |
|---|
| Mechanism of action | Leukotriene receptor antagonist |
|---|
All known targets
Mechanisms of action (all sources)
- Leukotriene receptor antagonist
- CYSLTR1 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB11
- ALOX15
- USP1
- TSHR
- TDP1
- TARDBP
- RXRA
- RAPGEF4
- PPARG
- PPARD
- NFE2L2
- LMNA
- HDAC6
- GNAS
- GMNN
- GLS
- GLA
- ESR1
- ERG
- EHMT2
- CYP3A4
- AR
- ALOX5
- VDR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- CP1A2
- RPGF4
- RPGF3
- RAPGEF3
- PRGR
- NR1I2
- LRC26
- KCMB2
- KCMB1
- GPR32
- GCR
- CYSLTR2
- CP3A7
- CP3A4
- CP2CJ
- CP2C9
- TP53
Drug classes
Cross-references
Synonyms
- LY-171833
- LY-171883
- LY171883
- Tomelukastum
- Lilly 171883
- DTXCID30344
- CHEBI:75310
- RefChem:898607
- Tomelukastum [INN-Latin]
- Compound LY171883
- MLS000069512
- NCGC00018122-08
- SMR000058555
- Tomelukast [USAN:INN]
- CAS-88107-10-2
- SR-05000000448
- BRN 4238438
- UNII-59762X5CLS
- MWYHLEQJTQJHSS-UHFFFAOYSA-N
- CPD000058555
- TOMELUKAST [INN]
- Opera_ID_1639
- Spectrum3_001918
- Spectrum5_001969
- Spectrum5_002024
- Tomelukast (USAN/INN)
- TOMELUKAST [USAN]
- SCHEMBL3944
- TOMELUKAST [MART.]
- CBiol_001912
- BSPBio_001402
- BSPBio_003516
- KBioGR_000122
- KBioSS_000122
- MLS000758272
- MLS001423988
- BML2-G05
- SCHEMBL5325407
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