← SynDRA
PROCARBAZINE
SynDRA canonical compound SYN0005260 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | monoamine oxidase inhibitor |
|---|
| Indication | Hodgkin's lymphoma |
|---|
| Disease area | hematologic malignancy |
|---|
Mechanisms of action (all sources)
- monoamine oxidase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PTGS2
- NPY1R
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KDM4A
- ACHE
- KCNH2
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH2
- HRH1
- HMGCR
- HDAC6
- GMNN
- MMP9
- NPY2R
- GHSR
- PTPRC
- USP1
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLC6A4
- SLC6A3
- SLC6A2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACES
- ALOX12
- CP1A2
- CP2CJ
- CP2D6
- KCMA1
- LOX12
- LOX15
Drug classes
- Alkylating Activity
- Alkylating Drug
- Antineoplastic Agents
ATC classes
- L01X · OTHER ANTINEOPLASTIC AGENTS
Cross-references
Synonyms
- MATULANE
- Matulane
- ibenzmethyzine
- procarbazine hydrochloride
- procarbazine HCl
- Procarbazina
- Procarbacine
- RO-4-6467
- RO-4-6467 FREE BASE
- Ibenzmethyzin
- Ibenzmethyzine
- MBH
- MIH
- Natulan
- Natulanar
- PCX
- Procarbazin
- Procarbazinum
- Procarbazin [German]
- Procarbazine Monohydrochloride
- CB 400-497
- Indicarb (TN)
- Matulane (TN)
- Natulan (TN)
- Procarbazina [INN-Spanish]
- Procarbazine (INN)
- Procarbazine [INN:BAN]
- Procarbazinum [INN-Latin];Ro 4-6467
- SRI-10847
- Ro 4-6467/1
- N-4-Isopropylcarbamoylbenzyl-N'-methylhydrazine
- N-Isopropyl-4-[(2-methylhydrazino)methyl]benzamide
- P-(2-Methylhydrazinomethyl)-N-isopropylbenzamide
- N-Isopropyl-p-(2-methylhydrazinomethyl)-benzamide
- P-(N'-Methylhydrazinomethyl)-N-isopropylbenzamide
- N-(1-Methylethyl)-4-[(2-methylhydrazino)methyl]benzamide
- N-Isopropyl-alpha-(2-methylhydrazino)-p-toluamide
- N-(1-Methylethyl)-4-((2-methylhydrazino)methyl)benzamide
Reported adverse events
- Nausea
- Coma
- Hallucination
- Hodgkin's disease
- Hypotension
- Leukopenia
- Pain
Look up PROCARBAZINE in the interactive SynDRA portal →