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TIOPRONIN
SynDRA canonical compound SYN0005235 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | chelating agent | reducing agent |
|---|
| Indication | kidney stones |
|---|
| Disease area | urology |
|---|
All known targets
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- PTGS2
- ABCB1
- NR1I2
- HTR1A
- HTR2A
- HTR2B
- HTR2C
- HTR3A
- KCNH2
- LMNA
- MAOA
- MAPT
- MC3R
- MLNR
- NR3C1
- ABCC1
- OPRD1
- OPRM1
- PDE3A
- PDE4D
- PGR
- PPARG
- SLC29A1
- SLC6A2
- SLC6A3
- SLC6A4
- HRH3
- HRH1
- HDAC6
- GHSR
- ADORA1
- ADORA2A
- ADORA3
- ADRA1A
- ADRA2A
- ADRA2B
- ADRA2C
- ADRB1
- ADRB2
- AGTR1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Cystine Disulfide Reduction
- Reducing and Complexing Thiol
- chelating agent
- reducing agent
ATC classes
Cross-references
Synonyms
- THIOLA
- THIOLA EC
- Thiola
- VENXXIVA
- Venxxiva
- (+/-)-Tiopronin
- acadione
- capen
- captimer
- hepadigest
- mercaptopropionylglycine
- thiolpropionamidoacetic acid
- thiopronin
- thiopronine
- tiopronine
- alpha-Mercaptopropionylglycine
- Tiopronine
- Tiopronina
- NSC-760416
- Acadione
- Captimer
- Thiola ec
- Thiota (TN)
- MERCAPTOPROPIONYLGLYCINE-
- Glycine, N-(2-mercapto-1-oxopropyl)-
- N-(2-Mercaptopropionyl)glycine
- C5W04GO61S
- NSC 760416
- Thiopronine
- 2-(2-sulfanylpropanoylamino)acetic acid
- Thiolpropionamidoacetic acid
- tiopronina
- Tioproninum
- (2-Mercaptopropionyl)glycine
- DTXCID803678
- alpha Mercaptopropionylglycine
- 2-Mercaptopropionylglycine
Reported adverse events
- Hypersensitivity
- Hypogeusia
- Proteinuria
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