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FOMEPIZOLE
SynDRA canonical compound SYN0005190 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | ADH1C |
|---|
| Mechanism of action | Alcohol dehydrogenase inhibitor |
|---|
| Indication | poison antidote |
|---|
| Disease area | critical care |
|---|
All known targets
- ADH1A
- ADH1B
- ADH1C
- AKR1A1
- CAT
Mechanisms of action (all sources)
- Alcohol dehydrogenase inhibitor
- ADH1A INHIBITOR
- ADH1B INHIBITOR
- ADH1C INHIBITOR
- ADH1A MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- ADORA1
- NPY2R
- NPY1R
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LMNA
- LCK
- KDM4A
- KCNH2
- KAT2A
- HTR6
- HTR3A
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH2
- HRH1
- NR1I2
- NR3C1
- OPRD1
- PTPRC
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SNCA
- SLC6A4
- SLC6A3
- SLC6A2
- SLC29A1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Antidote
- Antidotes
- Enzyme Inhibitors
- Protective Agents
ATC classes
- V03A · ALL OTHER THERAPEUTIC PRODUCTS
Cross-references
Synonyms
- ANTIZOL
- homepizoru
- 4-methylpyrazole
- antizol
- Fomepizol
- 4-MP
- NSC-760365
- Antizol
- Fomepizolum
- Orphan brand of fomepizole
- Paladin brand of fomepizole
- M0774
- Antizol (TN)
- Fomepizol [INN-Spanish]
- Fomepizole [USAN:INN]
- Fomepizolum [INN-Latin]
- S14-0570
- Fomepizole (USAN/INN)
- 4-Methyl-1H-pyrazole
- 4-Methylpyrazol
- 4-Methylpyrazole
- 4-methylpyrazole monohydrochloride
- NSC 760365
- 1H-Pyrazole, 4-methyl-
- CHEBI:5141
- 4 Methylpyrazole Monohydrochloride
- RefChem:58530
- DTXCID1020649
- V03AB34
- Antizol-vet
- PYRAZOLE, 4-METHYL-
- MFCD00005245
- 4-methyl-pyrazole
- EINECS 231-445-0
- UNII-83LCM6L2BY
- BRN 0105204
- Fomepizole [USAN:INN:BAN]
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