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QUININE
SynDRA canonical compound SYN0005133 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | KCNN4 |
|---|
| Mechanism of action | Hemozoin biocrystallization inhibitor |
|---|
| Indication | malaria |
|---|
| Disease area | infectious disease |
|---|
All known targets
- KCNB2
- KCNN4
- SLC29A4
- ABCB1
- GP9
- HBA1
- KCNH2
- SCN1A
- SCN2A
- SCN3A
- SLC22A1
Mechanisms of action (all sources)
- Hemozoin biocrystallization inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- OPRM1
- ADRA2A
- SLC22A2
- CYP2D6
- ESR1
- ABCB11
- SLC22A4
- PDE3A
- PDE4A
- PGR
- POLI
- PTGS1
- SLC22A3
- SLC22A5
- KDR
- SLC2A1
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B1
- SLCO1B3
- SMAD3
- TBXA2R
- MAOA
- KCNK3
- KCNK9
- ABCC2
- ACHE
- ADORA3
- ADRA1A
- ALB
- AR
- CHRM1
- CHRM2
- CYP3A4
- DRD1
- DRD3
- F2
- HDAC6
- HRH3
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- AHR
- ANDR
- CP1A2
- CP2CJ
- CP2D6
- GCR
- GLI3
- IFNG
- KCNK2
- S29A4
Drug classes
- Antimalarial
- Analgesics
- Analgesics, Non-Narcotic
- Anti-Infective Agents
- Antimalarials
- Antiparasitic Agents
- Antiprotozoal Agents
- Central Nervous System Agents
- Muscle Relaxants, Central
- Neuromuscular Agents
- Peripheral Nervous System Agents
- Sensory System Agents
ATC classes
- M09A · OTHER DRUGS FOR DISORDERS OF THE MUSCULO-SKELETAL SYSTEM
- P01B · ANTIMALARIALS
Cross-references
Synonyms
- QUALAQUIN
- QUININE SULFATE
- Qualaquin
- quinine bisulfate heptahydrate
- chinine
- qualaquin
- quinine sulfate
- (8s,9r)-6'-methoxycinchonan-9-ol
- Chininum purum
- Rezquin
- NSC-192949
- WR297608
- Aflukin
- Chinin
- Chinine
- Chininum
- Conchinin
- Conquinine
- Quindan
- Quinidex
- Quinidine
- Quinimax
- Quinina
- Quinineanhydrous
- Quinora
- Quniacridine
- Chinin [German]
- Kinder Quinina
- QUININE MONO HCL
- Quinine Dab
- Quinine [BAN]
- Quinine anhydrous
- Quinine bisulfate
- Quinine sulfate
- Quinine sulphate
- Quinoline alkaloid
- LT00645788;Q0028
- SB01652
Reported adverse events
- Chronic renal impairment
- Stevens-Johnson syndrome
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