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QUINIDINE
SynDRA canonical compound SYN0005100 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | SCN5A |
|---|
| Mechanism of action | Sodium channel blocker |
|---|
| Indication | atrial fibrillation (AF) | malaria | ventricular arrhythmias |
|---|
| Disease area | cardiology | infectious disease |
|---|
All known targets
- SCN5A
- SCN1A
- SCN3A
- SCN2A
- SCN10A
- SLC29A4
- SCN9A
- SCN8A
- SCN7A
- SCN4A
- SCN11A
- ABCB1
Mechanisms of action (all sources)
- Sodium channel blocker
- SCN1A BLOCKER
- Sodium channel alpha subunit blocker
- SCN5A BLOCKER
- SCN4A BLOCKER
- SCN7A BLOCKER
- SCN2A BLOCKER
- SCN9A BLOCKER
- SCN3A BLOCKER
- SCN11A BLOCKER
- SCN8A BLOCKER
- SCN10A BLOCKER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR2A
- SLC6A3
- OPRM1
- NR1I2
- HTR2B
- CACNA1C
- DRD2
- SLC22A1
- DRD3
- ESR1
- OPRK1
- SLC6A4
- ADRA2B
- ADRA1A
- MLNR
- HTR2C
- NR3C1
- HTR3A
- INPP5D
- NPY1R
- NFE2L2
- INPPL1
- KCNQ2
- KCNK9
- KCNMA1
- MC4R
- OPRD1
- MAOA
- MC3R
- ABCB11
- PDE3A
- SLC47A2
- TSHR
- TDP1
- SLCO2B1
- SLCO1B3
- SLCO1B1
- SLCO1A2
- SLC6A2
- SLC29A1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- AHR
- CACNA1D
- CACNA1F
- CACNA1S
- CP2D6
- CP3A7
- ESRRA
- IFNG
- KCNK5
- KCNKG
- KCNU1
- S29A4
Drug classes
- Antiarrhythmic
- Anti-Infective Agents
- Antimalarials
- Antiparasitic Agents
- Antiprotozoal Agents
- Adrenergic Agents
- Adrenergic alpha-Antagonists
- Adrenergic Antagonists
- Anti-Arrhythmia Agents
- Cardiovascular Agents
- Cholinergic Agents
- Cholinergic Antagonists
ATC classes
- C01B · ANTIARRHYTHMICS, CLASS I AND III
Cross-references
Synonyms
- CARDIOQUIN
- CIN-QUIN
- DEXTROMETHORPHAN HYDROBROMIDE AND QUINIDINE SULFATE
- DURAQUIN
- NUEDEXTA
- QUINACT
- QUINAGLUTE
- QUINALAN
- QUINATIME
- QUINIDEX
- QUINIDINE GLUCONATE
- QUINIDINE SULFATE
- quincardine
- quinidine polygalacturonate
- quinidine sulfate dihydrate
- quinidine sulfate
- quinidine gluconate
- chinidin
- conchinin
- conchinine
- conquinine
- quindine
- pitayine
- beta-Quinidine
- quinidine hydrochloride monohydrate
- quinidine hydrochloride
- quinidine HCl
- (8r,9s)-quinidine
- .beta.-quinidine
- Conquinine
- Kinidin
- Pitayine
- (+)-Quinidine
- Conchinin
- Chinidin
- (8R,9S)-Quinidine
- Quinidex
- beta-Quinine
Reported adverse events
- Vomiting
- Cinchonism
- Asthenia
- Dizziness
- Flatulence
- Influenza
- Cough
- Urinary tract infection
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