← SynDRA

INDOLE-3-CARBINOL

SynDRA canonical compound SYN0005056 — structure-anchored drug synonym record

All known targets

• AHR
• IDO1
• NFKBIA

Mechanisms of action (all sources)

• aryl hydrocarbon receptor agonist
• indoleamine 2,3-dioxygenase inhibitor
• NFKBIA INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• CXCL8
• EHMT2
• ESR1
• GMNN
• GPR84
• HDAC6
• NFE2L2
• PIN1
• RORC
• SLCO1B1
• SLCO1B3
• TDP1

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• ACM1
• GLI3
• SYK
• PRGR
• PPARG
• NSD2
• NR1I2
• NF2L2
• KSYK
• IP6K1
• ESRRA
• ANDR
• ESR2
• CP3A7
• CP3A4
• CP2D6
• CP2CJ
• CP2C9
• CP1A2
• CP19A
• TP53

Drug classes

• Anticarcinogenic Agents

Cross-references

• PubChem CID: 3712
• ChEMBL: CHEMBL155625
• DrugBank: DB12881
• ChEBI: 24814
• RxNorm: 2598119
• PDB: FXK
• Wikipedia: Indole-3-carbinol
• TTD: DN62DG
• LINCS BRD: BRD-K01815685

Synonyms

• NSC-525801
• I3C
• Indole 3 carbinol
• 3-Indolemethanol
• INDOLE-3-METHANOL
• (1H-Indol-3-yl)methanol
• 1H-indol-3-ylmethanol
• 3-Hydroxymethylindole
• 1H-Indole-3-methanol
• 3-Indolylcarbinol
• Indinol
• 3-(Hydroxymethyl)indole
• 3-Indole methanol
• (1H-Indol-3-yl)-methanol
• MFCD00005632
• UNII-C11E72455F
• CHEBI:24814
• C11E72455F
• NSC 525801
• NCGC00090701-06
• indol-3-ylmethan-1-ol
• I0496
• Indole-3-carbinol, 97%
• SMR000385784
• CCRIS 3261
• EINECS 211-836-2
• 1H-Indol-3-Yl-Methanol
• BRN 0121323
• AI3-60090
• 3-Indolecarbinol
• 3-Indolylmethanol
• Prevention 4 (indole-3-carbinol)
• indole-3-carbinole
• zlchem 356
• PubChem7265
• 3-hydroxymethyl indole
• Spectrum2_001710
• Spectrum3_001973
• ACMC-209oc7