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FROVATRIPTAN
SynDRA canonical compound SYN0005003 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | HTR1A | HTR1B | HTR1D |
|---|
| Mechanism of action | serotonin receptor agonist |
|---|
| Indication | migraine headache |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
Mechanisms of action (all sources)
- HTR1B AGONIST
- Serotonin 1b (5-HT1b) receptor agonist
- HTR1D AGONIST
- Serotonin 1d (5-HT1d) receptor agonist
- serotonin receptor agonist
- HTR1B MODULATOR
- HTR1D MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- DRD2
- HTR1E
- DRD4
- HTR7
- OPRM1
- TMEM97
- ADRA1B
- HTR6
- HTR5A
- MBD4
- MUTYH
- NEIL1
- NEIL2
- NTHL1
- OGG1
- OPRD1
- OPRK1
- MPG
- ADGRF1
- HTR2C
- POU2F1
- POU2F2
- S1PR1
- SIGMAR1
- SLC22A3
- SLC47A1
- SLC47A2
- SLC6A2
- SLC6A4
- SMUG1
- TDG
- TSPO
- HTR3A
- HTR2A
- HTR2B
- ADRA1A
- ADRA1D
- ADRA2A
- ADRA2B
- ADRB1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Neurotransmitter Agents
- Serotonin Agents
- Serotonin Receptor Agonists
- Serotonin 1b Receptor Agonists
- Serotonin 1d Receptor Agonists
- Serotonin-1b and Serotonin-1d Receptor Agonist
ATC classes
- N02C · ANTIMIGRAINE PREPARATIONS
Cross-references
Synonyms
- FROVA
- FROVATRIPTAN SUCCINATE
- Frova
- (R)-Frovatriptan
- frovatriptan succinate
- frovatriptan succinate hydrate
- SB 209509
- VML251
- Allergo filmtabletten
- Migard
- Mylatrip
- Allegro
- Auradol
- Frovelan
- Miguard
- Rilamig
- SB-209509
- Allergo filmtabletten(TN)
- Frova (TN)
- Frovatriptan (INN)
- H82Q2D5WA7
- miguard
- 3-methylamino-6-carboxamido-1,2,3,4-tetrahydrocarbazole
- frovatriptanum
- RefChem:56375
- DTXCID703080
- N02CC07
- frova
- FROVATRIPTAN [INN]
- R-Frovatriptan
- HSDB 7363
- Frovatriptan [INN:BAN]
- UNII-H82Q2D5WA7
- FROVATRIPTAN [MI]
- FROVATRIPTAN [HSDB]
- Allergo filmtabletten (TN)
- (R)-Frovatriptan;SB209509;SB-209509;SB 209509
- FROVATRIPTAN [VANDF]
Reported adverse events
- Dizziness
- Fatigue
- Chest pain
- Dyspepsia
- Flushing
- Seizure
- Arrhythmia
- Dry mouth
- Headache
- Heart rate
- Hypersensitivity
- Pain
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