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REPAGLINIDE
SynDRA canonical compound SYN0004980 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | ABCC8 |
|---|
| Mechanism of action | Insulin secretagogue |
|---|
| Indication | diabetes mellitus |
|---|
| Disease area | endocrinology |
|---|
All known targets
- ABCC8
- KCNJ11
- ABCC9
- CYP2C8
- CYP3A5
- INS
- PPARG
- SLC22A1
- SLCO1B1
Mechanisms of action (all sources)
- Insulin secretagogue
- KCNJ11 BLOCKER
- Sulfonylurea receptor 1, Kir6.2 blocker
- ABCC8 BLOCKER
- ABCC9 BLOCKER
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ABCB11
- DRD3
- NR1H4
- PDE4D
- NR1I3
- CYP3A4
- HTR2A
- HTR3A
- KAT2A
- HTR2C
- KCNH2
- LMNA
- HTR2B
- MAOA
- MAPK1
- MC3R
- MLNR
- NFE2L2
- NR1H2
- NR1H3
- HTR1A
- NR1I2
- ABCB1
- HRH3
- OPRD1
- TRIM24
- SLCO2B1
- SLCO1B3
- SLC6A4
- SLC6A3
- SLC6A2
- SLC29A1
- SAMHD1
- RARG
- RARB
- RARA
- RAPGEF4
- PTGS2
- PPARA
- PGR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ANDR
- CP3A7
- GCR
- GPR151
- KCMA1
- KCMB1
- KCMB2
- KCMB4
Drug classes
- Glinide
- Potassium Channel Antagonists
- Hypoglycemic Agents
ATC classes
- A10B · BLOOD GLUCOSE LOWERING DRUGS, EXCL. INSULINS
Cross-references
Synonyms
- PRANDIMET
- PRANDIN
- REPAGLINIDE AND METFORMIN HYDROCHLORIDE
- (S)-(+)-Repaglinide
- prandin
- enyglid
- surepost
- REPAGLINIDA
- A10BX02
- AG-EE 388 ZW
- AG-EE-623-ZW
- AG-EE-623ZW
- AGEE-623ZW
- CHEMBL1272
- Enyglid
- Novonorm
- NSC-759893
- Prandin
- Repaglinide accord
- Repaglinide component of prandimet
- Repaglinide krka
- Repaglinide teva
- Actulin
- GlucoNorm
- NovoNorm
- Repaglinida
- Repaglinidum
- Glaxo Wellcome brand of replaginide
- Novo Nordisk brand of repaglinide
- Repaglinide [USAN]
- Novo Nordisk brand 2 of repaglinide
- AG-EE-388
- AG-EE-623 ZW
- GlucoNorm (TN)
- NN-623
- NovoNorm (TN)
- Prandin (TN)
Reported adverse events
- Nausea
- Vomiting
- Arthralgia
- Chest pain
- Constipation
- Dyspepsia
- Urinary tract infection
- Death
- Sinusitis
- Alopecia
- Pancreatitis
- Bronchitis
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