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VARESPLADIB

SynDRA canonical compound SYN0004978 — structure-anchored drug synonym record

All known targets

• PLA2G2A
• PLA2G1B
• PLA2G2D

Mechanisms of action (all sources)

• Secretory phospholipase inhibitor
• PLA2G2A INHIBITOR
• Phospholipase A2 group IIA inhibitor

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• PLA2G10
• PLA2G12A
• PLA2G2E
• PLA2G2F
• PLA2G3
• PLA2G5
• PLA2G6
• HDAC6

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• PLA2G12B
• PLA2G2C

Cross-references

• PubChem CID: 155815
• ChEMBL: CHEMBL148674
• DrugBank: DB11909
• ChEBI: 189668
• KEGG: D08107
• PDB: VRD
• Wikipedia: Varespladib
• TTD: D74PRE
• LINCS BRD: BRD-K09711437

Synonyms

• Varepladib
• Varespladib sodium
• LY-315920
• LY315920
• ((3-(AMINO(OXO)ACETYL)-1-BENZYL-2-ETHYL-1H-INDOL-4-YL)OXY)ACETIC ACID
• ((3-(Aminooxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yl)oxy)acetic acid
• ((3-(aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl)oxy)acetate
• ({3-[amino(oxo)acetyl]-1-benzyl-2-ethyl-1H-indol-4-yl}oxy)acetic acid
• (3-Aminooxalyl-1-benzyl-2-ethyl-1H-indol-4-yloxy)-acetic acid
• (3-Aminooxalyl-1-benzyl-2-ethyl-2,3-dihydro-1H-indol-4-yloxy)-acetic acid
• 2-((3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yl)oxy)acetic acid
• 2-(1-benzyl-2-ethyl-3-oxamoylindol-4-yl)oxyacetic acid
• 2-(3-(2-amino-2-oxoacetyl)-1-benzyl-2-ethyl-1H-indol-4-yloxy)acetic acid
• 2-[[3-(2-Amino-2-oxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetic aci
• 2-[[3-(2-Amino-2-oxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl]oxy]acetic acid
• 2-[2-ethyl-3-oxamoyl-1-(phenylmethyl)indol-4-yl]oxyethanoic acid
• 2-{[1-benzyl-3-(carbamoylcarbonyl)-2-ethyl-1H-indol-4-yl]oxy}acetic acid
• 2Q3P98DATH
• A-001
• A25228
• AC-32931
• ACETIC ACID, ((3-(AMINOOXOACETYL)-2-ETHYL-1-(PHENYLMETHYL)-1H-INDOL-4-YL)OXY)-
• Acetic acid, ((3-(aminooxoacetyl)-2-ethyl-1-(phenylmethyl)-1H-indol-4-yl)oxy)-,
• AKOS015842901
• AMY19698
• AS-16956
• BCP01854
• BCP9000883
• BCPP000175
• BDBM50055366
• BRD-K09711437-001-01-9
• CCG-268404
• CHEBI:189668
• CHEMBL148674
• compound 6m [PMID: 8978844]
• D08107
• DB11909
• DTXSID50169378
• EN300-144829