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PENTOLINIUM
SynDRA canonical compound SYN0004963 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | CHRNA10 | CHRNA3 | CHRNA4 | CHRNB4 |
|---|
| Mechanism of action | cholinergic receptor antagonist |
|---|
| Indication | hypertension |
|---|
| Disease area | cardiology |
|---|
All known targets
- CHRNA3
- CHRNB4
- CHRNA10
- CHRNA4
Mechanisms of action (all sources)
- CHRNB4 ANTAGONIST
- Neuronal acetylcholine receptor; alpha3/beta4 antagonist
- CHRNA3 ANTAGONIST
- cholinergic receptor antagonist
- CHRNA4 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- PTGS1
- KDR
- LMNA
- MAOA
- OPRM1
- PDE3A
- PDE4A
- PGR
- PMP22
- RGS4
- KAT2A
- SAMHD1
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B1
- SLCO1B3
- TBXA2R
- TDP1
- KCNH2
- HTR2B
- ADORA3
- CYP2C9
- ADRA1A
- ADRA2A
- AR
- BLM
- CHRM1
- CHRM2
- CYP1A2
- CYP2C19
- CYP2D6
- HTR1A
- CYP3A4
- DRD1
- DRD3
- EHMT2
- ESR1
- F2
Drug classes
- Antihypertensive Agents
- Cardiovascular Agents
- Cholinergic Agents
- Cholinergic Antagonists
- Ganglionic Blockers
- Neurotransmitter Agents
- Nicotinic Antagonists
- Peripheral Nervous System Agents
Cross-references
Synonyms
- ANSOLYSEN
- pentolonium
- pentapyrrolidinium
- pentolonium tartrate
- ansolysen
- pentolinium tartrate
- pentolinium bitartrate
- Pentolinium cation
- Pentolinium ion
- Pentolonium
- Pentolineum
- Pentolonum
- 1,1'-pentane-1,5-diylbis(1-methylpyrrolidinium)
- pentolineum
- pentolinium ion
- ULL76WPU5X
- CHEBI:347401
- RefChem:860063
- DTXCID5028110
- UNII-ULL76WPU5X
- PENTOLONIUM [WHO-DD]
- 1,1/'-(Pentamethylene)bis(1-methylpyrrolidinium)
- SCHEMBL210048
- CCG-204970
- NCGC00094207-05
- AB00053826
- NS00041352
- BRD-K44942604-322-01-4
- BRD-K44942604-346-04-7
- BRD-K44942604-346-05-4
- ペントリニウム
- CCG-222192
- EN300-754676
- Pentolinium di[L(+)-tartrate]
- SCHEMBL29479382
- Pentalinium tartrate
- Pentolinium bitartrate
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