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TETRAHYDROZOLINE
SynDRA canonical compound SYN0004952 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Mechanism of action | adrenergic receptor agonist |
|---|
| Indication | eye irritation |
|---|
| Disease area | ophthalmology |
|---|
All known targets
- ADRA2C
- ADRA1A
- ADRA1B
- ADRA1D
- ADRA2B
- ADRA2A
- Adra1a
- Adra1b
- Adra1d
- Adra2a
- Adra2b
- Adra2c
Mechanisms of action (all sources)
- ADRA1A AGONIST
- Adrenergic receptor alpha agonist
- ADRA2A AGONIST
- ADRA2C AGONIST
- ADRA1D AGONIST
- ADRA1B AGONIST
- ADRA2B AGONIST
- TADA2A AGONIST
- adrenergic receptor agonist
- ADRA2C MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR1A
- ACHE
- POLK
- IDH1
- KCNH2
- KDR
- MAOA
- OPRM1
- PDE3A
- PDE4A
- PGR
- PTGS1
- RGS4
- SAMHD1
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B1
- SLCO1B3
- TAAR1
- HTR2B
- HRH3
- ADORA3
- CYP2C19
- ALDH1A1
- AR
- ARSA
- BLM
- CBX1
- CHRM1
- CHRM2
- CYP1A2
- CYP2C9
- HDAC6
- CYP2D6
- CYP3A4
- DRD1
- DRD3
- ESR1
- F2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Cardiovascular Agents
- Nasal Decongestants
- Ophthalmic Solutions
- Peripheral Nervous System Agents
- Pharmaceutical Solutions
- Respiratory System Agents
- Sympathomimetics
- Vasoconstrictor Agents
ATC classes
- S01G · DECONGESTANTS AND ANTIALLERGICS
- R01A · DECONGESTANTS AND OTHER NASAL PREPARATIONS FOR TOPICAL USE
Cross-references
Synonyms
- TYZINE
- tetryzoline
- tetrahydrozoline nitrate
- (+/-)-Tetrahydrozoline
- ocuzolin
- tetryzolin
- dl-Tetrahydrozoline
- tetrahydrozoline hydrochloride
- tetrahydrozeline hydrochloride
- tetrahydrozeline nitrate
- tetrahydrozoline HCl
- tetrahydrozeline HCl
- Tetryzoline
- Tetrizolina
- Caltheon
- Tyzine
- S9U025Y077
- Tetryzolinum
- CHEBI:28674
- (+-)-Tetrahydrozoline
- RefChem:390786
- DTXCID7027837
- R01AA06
- R01AB03
- S01GA02
- Tetryzolin
- Tyzanol
- (-)-Tetrahydrozoline
- Tetryzoline, (-)-
- Tetrahydrozoline, (-)-
- MFCD00216026
- P7M4KML3S8
- Tetryzoline (INN)
- Tetrahydrozolinum
- TETRYZOLINE [INN]
- Tetryzolinum [INN-Latin]
- Tetrizolina [INN-Spanish]
- HSDB 7471
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