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GLAFENINE
SynDRA canonical compound SYN0004950 — structure-anchored drug synonym record
| Clinical phase | Withdrawn |
|---|
| Primary target(s) | CFTR |
|---|
| Mechanism of action | DeltaF508-CFTR Corrector |
|---|
| Indication | pain relief |
|---|
| Disease area | Pulmonology |
|---|
All known targets
- CFTR
- PTGS1
- PTGS2
- ABCB11
- Abcb11
Mechanisms of action (all sources)
- DeltaF508-CFTR Corrector
- PTGS2 INHIBITOR
- Cyclooxygenase inhibitor
- PTGS1 INHIBITOR
- cystic fibrosis transmembrane conductance regulator inhibitor
- DeltaF508-CFTR Correctors
- deltaf508-cftr correctors, cystic fibrosis transmembrane conductance regulator inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- NR1I2
- PDE4A
- ADORA3
- TBXA2R
- KDR
- CHRM2
- CHRM1
- SLC29A1
- DRD3
- KCNH2
- PDE4D
- MAPK1
- MAOA
- KDM4E
- ACHE
- MC3R
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HSD17B10
- HRH3
- HTR3A
- OPRD1
- MLNR
- NR3C1
- NR4A2
- HPGD
- OPRM1
- PDE3A
- PGR
- PPARG
- SAMHD1
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B3
- TDP1
- HRH1
- GHSR
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CP2C9
- IL1B
- SMAD3
- SMAD2
- PRGR
- NSD2
- NF2L2
- MDR1
- HSPB1
- CP2CJ
- GLI3
- ESRRA
- CREB1
- CP3A7
- CP3A4
- CP2D6
- TSHR
Drug classes
- Analgesics
- Analgesics, Non-Narcotic
- Central Nervous System Agents
- Peripheral Nervous System Agents
- Sensory System Agents
ATC classes
- N02B · OTHER ANALGESICS AND ANTIPYRETICS
Cross-references
Synonyms
- alcidon
- dolomate
- glafenin
- glaphenin
- glaphenine
- glicafan
- glifanan
- glifanar
- glycerylaminophenaquine
- privadol
- glafenine hydrochloride
- glafenine HCl
- Glafenina
- Glafenin
- NSC-757808
- R-1707
- Glaphenine
- Glaphenin
- Glicafan
- Glifanan
- Glycerylaminophenaquine
- Glifan
- 2,3-Dihydroxypropyl 2-((7-chloroquinolin-4-yl)amino)benzoate
- Glafeninum
- 2,3-dihydroxypropyl 2-[(7-chloroquinolin-4-yl)amino]benzoate
- 2,3-Dihydroxypropyl N-(7-chloro-4-quinolyl) anthranilate
- CHEBI:31653
- NSC 757808
- RefChem:389007
- DTXCID1028102
- N02BG03
- Dolomate
- Glifanar
- MFCD00079326
- Privadol
- 1-GLYCERYL N-[7-CHLORO-4-QUINOLYL]ANTHRANILATE HYDROCHLORIDE
- 2,3-dihydroxypropyl 2-[(7-chloro-4-quinolyl)amino]benzoate
- Alicidon
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