← SynDRA

DACINOSTAT

SynDRA canonical compound SYN0004827 — structure-anchored drug synonym record

All known targets

• HDAC1
• HDAC2
• HDAC3
• HDAC4
• HDAC5
• HDAC6
• HDAC7
• HDAC8
• HDAC9

Mechanisms of action (all sources)

• histone deacetylase inhibitor
• HDAC1 INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• HDAC10
• HDAC11
• CYP3A4
• KCNH2

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• COMT
• GAMT
• GNMT
• HLAB
• HNMT
• IFNB1
• IFNG
• KSYK
• NNMT
• NSD2
• PARP1
• PNMT
• SYK

Cross-references

• PubChem CID: 6445533
• ChEMBL: CHEMBL356066
• DrugBank: DB17034
• ChEBI: 94063
• TTD: D0B3FV

Synonyms

• Laq-824
• LAQ824
• NVP-LAQ824
• LAQ-824
• LAQ824 (Dacinostat)
• UNII-V10P524501
• (E)-N-hydroxy-3-[4-[[2-hydroxyethyl-[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]prop-2-enamide
• CHEMBL356066
• V10P524501
• (2E)-N-hydroxy-3-[4-({(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino}methyl)phenyl]prop-2-enamide
• Dacinostat [INN]
• (E)-N-Hydroxy-3-[4-[[2-hydroxyethyl-[2-(1H-indol-3-yl)ethyl]amino]meth yl]phenyl]prop-2-enamide
• (2E)-N-hydroxy-3-(4-{[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl}phenyl)prop-2-enamide
• NVP-LAQ 824
• NVP-LAQ824, Dacinostat, LAQ824
• LBH539
• 2-Propenamide, N-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1H-indol-3-yl)ethyl]amino]methyl]phenyl]-, (2E)-
• Dacinostat (NVP-LAQ824, LAQ824)
• (2e)-n-hydroxy-3-[4-[[(2-hydroxyethyl)[2-(1h-indol-3-yl)ethyl]amino]methyl]phenyl]-2-propenamide
• LAQ824 (NVP-LAQ824,Dacinostat)
• (2E)-N-Hydroxy-3-(4-(((2-hydroxyethyl)(2-(1H-indol-3-yl)ethyl)amino)methyl)phenyl)propenamide
• (2E)-N-Hydroxy-3-(4-({(2-hydroxyethyl)(2-(1H-indol-3-yl)ethyl)amino}methyl)phenyl)propenamide
• 2-Propenamide, N-hydroxy-3-(4-(((2-hydroxyethyl)(2-(1H-indol-3-yl)ethyl)amino)methyl)phenyl)-, (2E)-
• DACINOSTAT [WHO-DD]
• SCHEMBL95240
• MLS006010418
• MLS006011098
• SCHEMBL181782
• GTPL7497
• LAQ824,NVP-LAQ824
• BDBM19428
• CHEBI:94063
• DTXSID50870351
• BCP01747
• EX-A2226
• ZINC1494627
• MFCD09970778
• s1095
• AKOS015899788