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TRIPELENNAMINE
SynDRA canonical compound SYN0004786 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | HRH1 |
|---|
| Mechanism of action | Histamine receptor antagonist |
|---|
| Indication | allergic rhinitis | asthma | urticaria |
|---|
| Disease area | allergy | pulmonary |
|---|
All known targets
Mechanisms of action (all sources)
- Histamine receptor antagonist
- HRH1 ANTAGONIST
- Histamine H1 receptor antagonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- SLC6A2
- KCNH2
- ADRA2A
- OPRK1
- ADRA2C
- HTR2A
- CHRM2
- DRD1
- NR1I2
- SLC6A4
- SLC6A3
- ACHE
- PDE3A
- OPRM1
- OPRD1
- NR3C1
- NPY1R
- MLNR
- MDH1
- MC4R
- MC3R
- MAPK1
- MAOA
- PDE4A
- PTGS1
- PDE4D
- TBXA2R
- UGT1A9
- UGT1A6
- UGT1A4
- UGT1A3
- UGT1A1
- TDP1
- SMN1
- PGR
- SLCO1B3
- SLCO1B1
- SLC29A1
- SAMHD1
- PTGS2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ABCB6
- CP2D6
- CP3A7
- JUN
- KCMA1
- PADI4
Drug classes
- Anti-Allergic Agents
- Histamine Agents
- Histamine Antagonists
- Histamine H1 Antagonists
- Neurotransmitter Agents
ATC classes
- R06A · ANTIHISTAMINES FOR SYSTEMIC USE
- D04A · ANTIPRURITICS, INCL. ANTIHISTAMINES, ANESTHETICS, ETC.
Cross-references
Synonyms
- PBZ
- PBZ-SR
- Re-Covr
- TRIPELENNAMINE HYDROCHLORIDE
- pyribenzamin
- pyribenzamine
- pyrinamine base
- tripelenamine
- tripelennamin
- tripelennamine citrate
- tripelennamine hydrochloride
- tripelennamine HCl
- Tripelenamina
- NSC-118946
- Benzoxale
- Cizaron
- Dehistin
- Piribenzil
- Pyribenzamin
- Pyribenzamine
- Pyridbenzamine
- Resistamine
- Tonaril
- Tripelannamine
- Tripelenamine
- Tripelennamin
- Tripelennamina
- Tripelennaminum
- Tripellenamine
- Triplennamine
- Vetibenzamina
- Pyrinamine base
- Tripelennamina [Italian]
- Tripelennamine [BAN]
- Tripelennamine [INN]
- Ts and Blues
- Pyribenzamine (TN)
- Pyristine (piristina)
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