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IRSOGLADINE
SynDRA canonical compound SYN0004758 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Primary target(s) | PDE4A |
|---|
| Mechanism of action | Phosphodiesterase inhibitor |
|---|
| Indication | peptic ulcer disease (PUD) |
|---|
| Disease area | gastroenterology |
|---|
All known targets
Mechanisms of action (all sources)
- Phosphodiesterase inhibitor
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- ACHE
- ADORA1
- NPY2R
- NPY1R
- MMP9
- MMP1
- MLNR
- MC5R
- MC4R
- MC3R
- MAPK3
- MAPK14
- MAPK1
- MAOA
- LCK
- KDM4A
- KCNH2
- HTR6
- HTR2C
- HTR2B
- HTR2A
- HTR1A
- HRH3
- HRH2
- HRH1
- HMGCR
- HDAC6
- NR1I2
- NR3C1
- OPRD1
- RAPGEF4
- VDR
- TTR
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SLC6A4
- SLC6A3
- SLC6A2
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
Drug classes
- Anti-Ulcer Agents
- Anticarcinogenic Agents
- Antineoplastic Agents
- Gastrointestinal Agents
- Protective Agents
- Radiation-Protective Agents
ATC classes
- A02B · DRUGS FOR PEPTIC ULCER AND GASTRO-OESOPHAGEAL REFLUX DISEASE (GORD)
Cross-references
Synonyms
- dicloguamine
- irsogladine maleate
- Irsogladina
- NSC-759836
- Gaslon N
- Irsogladine malate
- Irsogladine maleate
- MN-1695
- 6-(2,5-Dichlorophenyl)-1,3,5-triazine-2,4-diamine
- Irsogladinum
- QBX79NZC1D
- NSC 759836
- DCPDAT
- RefChem:148867
- 6-(2,5-dichlorophenyl)-2,4-diamino-1,3,5-triazine
- DTXCID6023999
- Irsogladine [INN]
- 1,3,5-Triazine-2,4-diamine, 6-(2,5-dichlorophenyl)-
- 2,4-Diamino-6-(2,5-dichlorophenyl)-1,3,5-triazine
- MFCD00866871
- 2,4-Diamino-6-(2,5-dichlorophenyl)-s-triazine
- Irsogladine (INN)
- Irsogladine, Irsogladine maleate
- Irsogladinum [Latin]
- 2',5'-dichlorobenzoguanamine
- Irsogladina [Spanish]
- SMR001550538
- UNII-QBX79NZC1D
- IRSOGLADINE [MI]
- SCHEMBL62215
- IRSOGLADINE [WHO-DD]
- MLS004774154
- MLS006010071
- orb1300670
- SCHEMBL29517870
- BDBM69900
- CHEBI:93307
- cid_5282435
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