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OXYBUTYNIN
SynDRA canonical compound SYN0004756 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | CHRM3 |
|---|
| Mechanism of action | Acetylcholine receptor antagonist |
|---|
| Indication | urinary incontinence |
|---|
| Disease area | urology |
|---|
All known targets
- CHRM3
- CHRM2
- CHRM1
- CHRM4
- CHRM5
- CYP2C19
- Chrm1
- Chrm2
- Chrm3
- DRD3
- HTR2B
- Pgrmc1
Mechanisms of action (all sources)
- Acetylcholine receptor antagonist
- CHRM3 ANTAGONIST
- Muscarinic acetylcholine receptor M3 antagonist
- CHRM2 ANTAGONIST
- Muscarinic acetylcholine receptor M2 antagonist
- CHRM1 ANTAGONIST
- CHRM2 INVERSE AGONIST
- CHRM4 ANTAGONIST
- CHRM5 ANTAGONIST
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- KCNH2
- ABCB11
- LCK
- NPSR1
- MMP9
- MMP1
- MC5R
- MC4R
- MC3R
- MBTD1
- MAPK3
- MAPK14
- MAPK1
- MAOA
- L3MBTL4
- NPY2R
- L3MBTL3
- L3MBTL1
- KDR
- IDH1
- HTR6
- HTR2C
- HTR2A
- HTR1A
- HRH3
- HRH2
- NPY1R
- NR3C1
- ACHE
- PTGS2
- TDP1
- TBXAS1
- TBXA2R
- TACR2
- TACR1
- SMPD1
- SLC6A4
- SLC22A1
- SAMHD1
- RECQL
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- ACM1
- ACM4
- ACM5
- CP2C9
- CP2D6
- CP3A4
- KCMA1
- KCMB4
- MDR1
- NR1I2
- RGS4
Drug classes
- Cholinergic Muscarinic Antagonists
- Cholinergic Agents
- Cholinergic Antagonists
- Muscarinic Antagonists
- Neurotransmitter Agents
- Parasympatholytics
- Peripheral Nervous System Agents
- Urological Agents
- Cholinergic Muscarinic Antagonist
ATC classes
Cross-references
Synonyms
- DITROPAN
- DITROPAN XL
- Ditropan
- GELNIQUE
- GELNIQUE 3%
- Gelnique
- OXYBUTYNIN CHLORIDE
- OXYTROL
- OXYTROL FOR WOMEN
- Oxytrol
- oxybutynin hydrochloride
- oxybutynin chloride
- oxytrol
- ditropan
- kentera
- oxybutynin HCl
- Oxybutynine
- Oxibutinina
- Contimin 2.5
- Contimin 5
- Cystrin
- Kentera
- Kentera (previously oxybutynin nicobrand)
- Lyrinel xl
- Oxytrol for women
- Promictuline
- Urimin
- Oxibutyninum
- Oxybutyninum
- Oxybutyninum [INN-Latin]
- Oxybutynine [INN-French]
- Oxybutinin
- Oxibutinina [INN-Spanish]
- Oxybutynin Base
- transdermal patch
- Lyrinel XL
- Oxybutynin [USAN:INN:BAN]
Reported adverse events
- Constipation
- Dizziness
- Dry mouth
- Urinary tract infection
- Dyspepsia
- Headache
- Insomnia
- Nausea
- Somnolence
- Nervousness
- Infection
- Amblyopia
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