TRAPIDIL

SynDRA canonical compound SYN0004689 — structure-anchored drug synonym record

Clinical phase	Launched
Primary target(s)	PDGFRA
Mechanism of action	PDGFR inhibitor
Indication	coronary artery disease (CAD)
Disease area	cardiology

All known targets

PDGFRA
FGFR3

Mechanisms of action (all sources)

PDGFR inhibitor
PDGFR tyrosine kinase receptor inhibitor
FGFR3 INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

ANDR
CP1A2
CP3A7
RAPGEF3
RAPGEF4
RPGF3
RPGF4

Drug classes

Cardiovascular Agents
Enzyme Inhibitors
Hematologic Agents
Phosphodiesterase Inhibitors
Platelet Aggregation Inhibitors
Vasodilator Agents

ATC classes

C01D · VASODILATORS USED IN CARDIAC DISEASES

Cross-references

PubChem CID: 5531
ChEMBL: CHEMBL132767
DrugBank: DB09283
ChEBI: CHEBI:32254
KEGG: D01220
RxNorm: 10735
PDB: K1S
Wikipedia: Trapidil
TTD: D0U2CV
LINCS BRD: BRD-K95763993

Synonyms

trapymine
trapymin
rocornal
avantrin
Rocornal
AR-12008
Trapymin
Avantrin
Trapymine
N,N-diethyl-5-methyl-[1,2,4]triazolo[1,5-a]pyrimidin-7-amine
Trapidilum [INN-Latin]
UNII-EYG5Y6355E
EINECS 239-434-2
BRN 0186842
7-Diethylamino-5-methyl-s-triazolo(1,5-a)pyrimidine
MLS000567667
EYG5Y6355E
N,N-Diethyl-5-methyl-(1,2,4)triazolo(1,5-a)pyrimidine-7-amine
(1,2,4)Triazolo(1,5-a)pyrimidin-7-amine, N,N-diethyl-5-methyl-
5-Methyl-7-diethylamino-s-triazolo-(1,5-a)-pyrimidine
NCGC00016715-01
SMR000154170
SU10991
[1,2,4]Triazolo[1,5-a]pyrimidin-7-amine,N,N-diethyl-5-methyl-
s-Triazolo(1,5-a)pyrimidin-7-amine, N,N-diethyl-5-methyl-
CAS-15421-84-8
7-(Diethylamino)-5-methyl-s-triazolo(1,5-a)pyrimidine
Trapidilum
[1,2,4]Triazolo[1,5-a]pyrimidin-7-amine, N,N-diethyl-5-methyl-
Trapidil [INN:BAN:JAN]
7-(DIETHYLAMINO)-5-METHYL-S-TRIAZOLO[1,5-A]PYRIMIDINE
Rocornal (TN)
Trapidil,(S)
MFCD00193104
Opera_ID_461
5-Methyl-7-diaethylamino-s-triazolo(1.5-a)pyrimidin [German]
TRAPIDIL [INN]
TRAPIDIL [JAN]

Look up TRAPIDIL in the interactive SynDRA portal →