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RAMELTEON
SynDRA canonical compound SYN0004660 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · Rx/OTC |
|---|
| Primary target(s) | MTNR1B |
|---|
| Mechanism of action | Melatonin receptor agonist |
|---|
| Indication | insomnia |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
Mechanisms of action (all sources)
- Melatonin receptor agonist
- MTNR1A AGONIST
- MTNR1B AGONIST
- MTNR1A MODULATOR
- MTNR1B MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR2B
- SIGMAR1
- ABCB11
- MAOA
- OGG1
- NEIL2
- NEIL1
- MPG
- MBD4
- HTR7
- OPRK1
- HTR5A
- HTR3A
- HTR2C
- HTR2A
- HTR1E
- HTR1D
- OPRD1
- OPRM1
- ACHE
- SLCO1B1
- TSPO
- TMEM97
- TDG
- TBXA2R
- SMUG1
- SLCO1B3
- SLC6A4
- PDE3A
- SLC6A3
- SLC6A2
- S1PR1
- PTGS1
- PGR
- PDE4A
- HTR1B
- HTR1A
- HRH3
- ADRA2C
- C5AR1
Drug classes
- Melatonin Receptor Agonists
- Melatonin Receptor Agonist
ATC classes
- N05C · HYPNOTICS AND SEDATIVES
Cross-references
Synonyms
- ROZEREM
- Rozerem
- rozerem
- TAK-375
- TAK375
- Ramelteon [USAN]
- Rozerem (TN)
- Ramelteon (JAN/USAN/INN)
- Rozerem, TAK-375, Ramelteon
- ramelteonum
- RefChem:55966
- N05CH02
- DTXCID301508624
- MFCD08067736
- SMR002544684
- SR-05000001957
- s1259
- UNII-901AS54I69
- HSDB 7787
- Ramelteon [USAN:INN:BAN:JAN]
- JEV
- Ramelteon (Standard)
- Ramelteon Impurity 72
- RAMELTEON [INN]
- RAMELTEON [JAN]
- RAMELTEON [HSDB]
- RAMELTEON [VANDF]
- Ramelteon (TAK-375)
- RAMELTEON [MART.]
- RAMELTEON [WHO-DD]
- SCHEMBL29237
- BSPBio_002318
- MLS003915619
- MLS006010029
- TAK-375SL
- SPECTRUM1505817
- GTPL1356
Reported adverse events
- Nausea
- Dizziness
- Fatigue
- Somnolence
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