← SynDRA
GTS-21
SynDRA canonical compound SYN0004654 — structure-anchored drug synonym record
| Clinical phase | Phase 1/Phase 2 |
|---|
| Primary target(s) | CHRNA7 |
|---|
| Mechanism of action | cholinergic receptor agonist |
|---|
All known targets
Mechanisms of action (all sources)
- CHRNA7 AGONIST
- Neuronal acetylcholine receptor protein alpha-7 subunit agonist
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- CHRNA1
- CHRNA3
- CHRNA4
- CHRNB1
- CHRNB2
- CHRNB4
- CHRND
- CHRNG
Cross-references
Synonyms
- 3-(2,4-dimethoxybenzylidene)anabaseine
- Dimethoxybenzylidene anabaseine
- Dmxb-a
- Gts 21
- DMXBA
- DMXB-Anabaseine
- GTS-21 (dihydrochloride)
- DMXB-A
- (E)-3-((2,4-Dimethoxyphenyl)methylene)-3,4,5,6-tetrahydro-2,3'-bipyridine dihydrochloride
- 2,3'-Bipyridine, 3-((2,4-dimethoxyphenyl)methylene)-3,4,5,6-tetrahydro-, dihydrochloride, (E)-
- DMBX-anabaseine
- DMBX-A
- AC1O5PJQ
- SCHEMBL2561893
- SCHEMBL12274790
- HY-14564A
- CS-5486
- SB16826
- BC654014
- AN-16572
- GTS-21, >
- LS-173500
- 3-(2,4-Dimethoxybenzylidene)anabaseine dihydrochloride
- 8S399XDN2K
- RefChem:1050205
- DTXCID901511689
- UNII-8S399XDN2K
- 2wnj
- 3 (2,4 dimethoxybenzylidene)anabaseine
- GTS21
- SCHEMBL316745
- orb1305200
- orb1705900
- SCHEMBL29366365
- BDBM86543
- GTPL11384
- CHEBI:188219
- 2,4-Dimethoxybenzylidene anabaseine
- EX-A5523
Look up GTS-21 in the interactive SynDRA portal →