← SynDRA

FORMESTANE

SynDRA canonical compound SYN0004602 — structure-anchored drug synonym record

All known targets

• CYP19A1

Mechanisms of action (all sources)

• CYP19A1 INHIBITOR

Bioactivity evidence (ChEMBL activities table — not curator-asserted)

• PGR
• NR1I2
• ESR1
• ADORA1
• MC3R
• OPRD1
• NR3C1
• NPY1R
• MLNR
• MAOA
• PDE3A
• KCNH2
• HTR3A
• HTR2C
• HTR2B
• HTR2A
• OPRM1
• PDE4D
• HSD17B7
• PTGS2
• SAMHD1
• SLC29A1
• SLC6A2
• SLC6A3
• SLC6A4
• SLCO1B1
• SLCO1B3
• SMN1
• TARDBP
• TBXA2R
• TDP1
• THRB
• HTR1A
• HRH3
• ADORA2A
• CCKAR
• ADORA3
• ADRA1A
• ADRA2A
• ADRA2B

Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)

• ANDR
• CP19A
• CP2CJ
• CP2D6
• CP3A4
• CP3A7
• ESRRA
• GLI3
• PRGR
• TSHR

Drug classes

• Antineoplastic Agents
• Aromatase Inhibitors
• Enzyme Inhibitors
• Estrogen Antagonists
• Hormone Antagonists
• Steroid Synthesis Inhibitors

ATC classes

• L02B · HORMONE ANTAGONISTS AND RELATED AGENTS

Cross-references

• PubChem CID: 11273
• ChEMBL: CHEMBL132530
• DrugBank: DB08905
• ChEBI: CHEBI:75172
• KEGG: D07260
• RxNorm: 15070
• Wikipedia: Formestane
• TTD: D0B6PZ

Synonyms

• lentaron
• Formestano
• 4-oh-androstene-3,17-dione
• CGP-32349
• NSC-282175
• Lentaron
• 4-Hydroxyandrost-4-ene-3,17-dione
• 4-Hydroxyandrostenedione
• CGP 32349
• Lentaron(R)
• 4-OH-A
• B, Aromatase inhibitor
• 4-Hydroxy-4-androstene-3,17-dione
• NSC 282175
• 17-dione
• 4-OHA
• Formestane [INN:BAN]
• UNII-PUB9T8T355
• CCRIS 7483
• ANDROST-4-ENE-3,17-DIONE, 4-HYDROXY-
• 4-Hydroxy-delta(sub 4)-androstenedione
• BRN 1889793
• MLS002153359
• MLS000028826
• PUB9T8T355
• CHEBI:75172
• 4-OHAD
• (8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-2,6,7,8,9,11,12,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17-dione
• 4-hydroxy-Delta(4)-androstenedione
• Formestane (INN)
• SMR000058722
• FORMESTANE [INN]
• (8R,9S,10R,13S,14S)-4-hydroxy-10,13-dimethyl-7,8,9,10,11,12,13,14,15,16-decahydro-1H-cyclopenta[a]phenanthrene-3,17(2H,6H)-dione
• CAS-566-48-3
• formestano
• formestanum
• SaveCream