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ETHOPROPAZINE
SynDRA canonical compound SYN0004573 — structure-anchored drug synonym record
| Clinical phase | Launched |
|---|
| Approval status | Approved · OTC |
|---|
| Primary target(s) | CHRM1 |
|---|
| Mechanism of action | Cholinergic receptor antagonist |
|---|
| Indication | Parkinson's Disease |
|---|
| Disease area | neurology/psychiatry |
|---|
All known targets
- CHRM1
- BCHE
- ACHE
- Chrm1
- Chrm2
- GRIN3A
- HRH1
- SLC22A1
Mechanisms of action (all sources)
- Butyrylcholinesterase inhibitor
- Cholinergic receptor antagonist
- CHRM1 ANTAGONIST
- Muscarinic acetylcholine receptor M1 antagonist
- HRH1 MODULATOR
Bioactivity evidence (ChEMBL activities table — not curator-asserted)
- HTR1A
- DRD1
- ADRA1A
- OPRM1
- DRD3
- KCNH2
- ADRA2A
- TBXA2R
- POLK
- KDR
- MAOA
- MAPK1
- MAPT
- USP1
- PDE3A
- PDE4A
- PGR
- TP53
- SMN1
- TDP1
- PTGS1
- KDM4E
- SAMHD1
- SLC6A2
- SLC6A3
- SLC6A4
- SLCO1B1
- SLCO1B3
- RGS4
- ADORA3
- HTR2B
- CYP2C19
- ALDH1A1
- ALOX12
- ALOX15
- ALOX15B
- AR
- ARSA
- ATXN2
- CBX1
Screening evidence (raw PubChem HTS — uncurated, known false-positive rate)
- 5HT2A
- ANDR
- CP1A2
- CP2CJ
- CP2D6
- CP3A4
- CP3A7
- GLSK
- JUN
- LOX12
- LOX15
- NTM1A
- RAPGEF4
- RPGF4
- UBP1
Drug classes
- Adrenergic Agents
- Adrenergic Antagonists
- Cholinergic Agents
- Cholinergic Antagonists
- Histamine Agents
- Histamine Antagonists
- Muscarinic Antagonists
- Neurotransmitter Agents
ATC classes
- N04A · ANTICHOLINERGIC AGENTS
Cross-references
Synonyms
- PARSIDOL
- profenamine
- profenamine hibenzate
- profenamine hydrochloride
- ethopromazine
- ethapropazine
- isopthazine
- isothazine
- isothiazine
- ethopropazine hydrochloride
- ethopropazine HCl
- Profenamine
- Profenamina
- RP-3356
- SC-2538
- W-483
- Aethopropropazin
- Athapropazine
- Athopropazin
- Ethapropazine
- Ethopromazine
- Etopropezina
- Fempropazine
- Fenpropazina
- Isopthazine
- Isotazin
- Isothazine
- Isothiazine
- Lysivane
- Parcidol
- Pardidol
- Parfezine
- Parkin
- Parkisol
- Parsidan
- Parsidol
- Parsitan
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